RALA gene

Known as: RAS-LIKE PROTEIN, RAS-like protein A, RALA 
This gene plays a role in signal transduction and mediates receptor signaling.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1977-2018
0102019772018

Papers overview

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Highly Cited
2007
Highly Cited
2007
Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide, accounting for an estimated 600,000 deaths annually… (More)
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Highly Cited
2007
Highly Cited
2007
The serine-threonine protein phosphatase 2A (PP2A) is a heterotrimeric enzyme family that regulates numerous signaling pathways… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND The Ral guanine nucleotide-exchange factors (RalGEFs) serve as key effectors for Ras oncogene transformation of… (More)
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Highly Cited
2005
Highly Cited
2005
RalGEFs were recently shown to be critical for Ras-mediated transformed and tumorigenic growth of human cells. We now show that… (More)
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Highly Cited
2004
Highly Cited
2004
RalA and RalB constitute a family of highly similar (85% identity) Ras-related GTPases. Recently, active forms of both RalA and… (More)
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Highly Cited
2003
Highly Cited
2003
Ral GTPases have been implicated in the regulation of a variety of dynamic cellular processes including proliferation, oncogenic… (More)
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Highly Cited
1996
Highly Cited
1996
Ral proteins (RalA and RalB) comprise a distinct family of Ras-related GTPases (Feig and Emkey, 1993). Recently, Ral-GDS, the… (More)
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Highly Cited
1995
Highly Cited
1995
Ral proteins constitute a distinct family of Ras-related GTPases. Although similar to Ras in amino acid sequence, Ral proteins… (More)
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Highly Cited
1995
Highly Cited
1995
AN early response to the tyrosine kinase activity of v-Src is an increase in phospholipase D (PLD) activity1, which leads to the… (More)
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Highly Cited
1994
Highly Cited
1994
The yeast two-hybrid system was used to identify proteins that interact with Ras. The H-Ras protein was found to interact with a… (More)
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