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RAG2 gene

Known as: RAG2, RECOMBINATION-ACTIVATING GENE 2, recombination activating gene 2 
This gene plays a role in immunoglobulin diversity.
National Institutes of Health

Related topics

Related topics

3 relations
Immune System ProcessesV(D)J RecombinationV(D)J recombination activating protein 2

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
The RAG transposon is active through the deuterostome evolution and domesticated in jawed vertebrates
RAG1 and RAG2 are essential subunits of the V(D)J recombinase required for the generation of the variability of antibodies and T… 
2015
2015
Erratum to: Molecular phylogeny of the subfamily Stevardiinae Gill, 1858 (Characiformes: Characidae): classification and the evolution of reproductive traits
Erratum The original version of this article unfortunately contained some mistakes. The presentation of Figs. 3–10 were incorrect… 
2002
2002
RAG2 Is Down-regulated by Cytoplasmic Sequestration and Ubiquitin-dependent Degradation*
Periodic accumulation and degradation of RAG2 (recombination-activating gene 2) protein controls the cell-cycle-dependent V(D)J… 
2000
2000
A highly ordered structure in V(D)J recombination cleavage complexes is facilitated by HMG1.
Central to understanding the process of V(D)J recombination is appreciation of the protein-DNA complex which assembles on the… 
Review
1999
Review
1999
RAG and RAG defects.
Highly Cited
1999
Highly Cited
1999
RAG2 is regulated differentially in B and T cells by elements 5' of the promoter.
To study RAG2 gene regulation in vivo, we developed a blastocyst complementation method in which RAG2-deficient embryonic stem… 
1998
1998
Distinct roles of the interleukin-7 receptor alpha chain in fetal and adult thymocyte development revealed by analysis of interleukin-7 receptor alpha-deficient mice.
Mouse mutants lacking expression of the IL-7 receptor (IL-7R) alpha chain are defective in thymopoiesis. The adult thymus has… 
1996
1996
In vitro V(D)J recombination: signal joint formation.
The first step of V(D)J recombination, specific cleavage at the recombination signal sequence (RSS), can be carried out by the… 
Highly Cited
1991
Highly Cited
1991
Expression of human recombination activating genes (RAG1 and RAG2) in neoplastic lymphoid cells: correlation with cell differentiation and antigen receptor expression.
Regulation of V-(D)-J recombinations that occur in antigen receptor encoding genes remains poorly understood. Recently, two genes… 
Highly Cited
1989
Highly Cited
1989
RAG1 and RAG2: Nuclear genes involved in the dependence/independence on mitochondrial respiratory function for growth on sugars
The analysis of five independent isolates of Kluyveromyces lactis shows that CBS 2359, CBS 683 and CBS 4574 could grow in the… 
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