RAG2 gene

Known as: RAG2, RECOMBINATION-ACTIVATING GENE 2, recombination activating gene 2 
This gene plays a role in immunoglobulin diversity.
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
The critical initial step in V(D)J recombination, binding of RAG1 and RAG2 to recombination signal sequences flanking antigen… (More)
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Highly Cited
2007
Highly Cited
2007
Nuclear processes such as transcription, DNA replication and recombination are dynamically regulated by chromatin structure… (More)
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Highly Cited
2007
Highly Cited
2007
Recombination activating gene (RAG) 1 and RAG2 together catalyze V(D)J gene rearrangement in lymphocytes as the first step in the… (More)
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Highly Cited
2005
Highly Cited
2005
Squamate reptiles number approximately 8000 living species and are a major component of the world's terrestrial vertebrate… (More)
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Highly Cited
2002
Highly Cited
2002
Previous in vitro studies defined the minimal regions of RAG1 and RAG2 essential for V(D)J recombination. In order to… (More)
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Highly Cited
2001
Highly Cited
2001
Omenn syndrome (OS) is an inherited disorder characterized by an absence of circulating B cells and an infiltration of the skin… (More)
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Highly Cited
1999
Highly Cited
1999
We generated mice in which a functional RAG2:GFP fusion gene is knocked in to the endogenous RAG2 locus. In bone marrow and… (More)
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Highly Cited
1997
Highly Cited
1997
During V(D)J recombination, RAG1 and RAG2 cleave DNA adjacent to highly conserved recombination signals, but nothing is known… (More)
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Highly Cited
1996
Highly Cited
1996
The products of the Rag1 and Rag2 genes drive genomic V(D)J rearrangements that assemble functional immunoglobulin and T cell… (More)
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Highly Cited
1995
Highly Cited
1995
Formation of double-strand breaks at recombination signal sequences is an early step in V(D)J recombination. Here we show that… (More)
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