Skip to search formSkip to main contentSkip to account menu

RAD9A protein, human

Known as: RAD9A, hrad9 protein, Cell Cycle Checkpoint Control Protein RAD9A 
Cell cycle checkpoint control protein RAD9A (391 aa, ~43 kDa) is encoded by the human RAD9A gene. This protein plays a role in DNA repair-dependent… 
National Institutes of Health

Related topics

Related topics

16 relations
3'-5'-ExonucleasesCell Cycle CheckpointsCell Cycle ControlDNA Repair

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Chk1 Activation Protects Rad9A from Degradation as Part of a Positive Feedback Loop during Checkpoint Signalling
Phosphorylation of Rad9A at S387 is critical for establishing a physical interaction with TopBP1, and to downstream activation of… 
2014
2014
hRAD9 functions as a tumor suppressor by inducing p21-dependent senescence and suppressing epithelial-mesenchymal transition through inhibition of Slug transcription.
Senescence and epithelial-mesenchymal transition (EMT) have opposing roles in tumor progression, in that, one is a barrier… 
2010
2010
The Rad9A checkpoint protein is required for nuclear localization of the claspin adaptor protein
The interaction between the 911 complex, via Rad9A, and Claspin is required for activation of the Chk1-mediated checkpoint… 
2008
2008
DNA damage sensor protein hRad9, a novel molecular target for lung cancer treatment.
DNA damage sensor proteins are recognized as upstream components of the DNA damage checkpoint signaling pathway and are required… 
2006
2006
His239Arg SNP of HRAD9 is associated with lung adenocarcinoma
It was previously reported that a functional human (h) Rad9 protein accumulated in the nuclei of nonsmall cell lung carcinoma… 
2004
2004
Human RAD 9 checkpoint control proapoptotic protein can activate transcription of p 21
When human cells incur DNA damage, two fundamental responses can follow, cell cycle arrest or apoptosis. Human RAD9 (hRAD9) and… 
2003
2003
Expression of mammalian paralogues of HRAD9 and Mrad9 checkpoint control genes in normal and cancerous testicular tissue.
Human and mouse paralogues of the evolutionarily conserved mammalian HRAD9 and Mrad9 cell cycle checkpoint control genes have… 
1999
1999
Identification of a human homologue of the Schizosaccharomyces pombe rad17(+) checkpoint gene. (vol 273, pg 18340, 1998)
Highly Cited
1998
Highly Cited
1998
Identification of a Human Homologue of theSchizosaccharomyces pombe rad17 + Checkpoint Gene*
In the fission yeast Schizosaccharomyces pombe the rad17 + gene is required for both the DNA damage-dependent and the DNA… 
1998
1998
Molecular cloning and tissue‐specific expression of Mrad9, a murine orthologue of the Schizosaccharomyces pombe rad9+ checkpoint control gene
We have isolated a murine cDNA, Mrad9, that is orthologous to the fission yeast rad9+ and human HRAD9 genes. Mrad9 encodes a 389… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)