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RAD9A protein, human
Known as:
RAD9A
, hrad9 protein
, Cell Cycle Checkpoint Control Protein RAD9A
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Cell cycle checkpoint control protein RAD9A (391 aa, ~43 kDa) is encoded by the human RAD9A gene. This protein plays a role in DNA repair-dependent…
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National Institutes of Health
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Related topics
Related topics
16 relations
3'-5'-Exonucleases
Cell Cycle Checkpoints
Cell Cycle Control
DNA Repair
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
The human checkpoint sensor Rad9–Rad1–Hus1 interacts with and stimulates DNA repair enzyme TDG glycosylase
Xin-min Guan
,
A. Madabushi
,
+4 authors
A. Lu
Nucleic Acids Research
2007
Corpus ID: 16909946
Human (h) DNA repair enzyme thymine DNA glycosylase (hTDG) is a key DNA glycosylase in the base excision repair (BER) pathway…
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Highly Cited
2006
Highly Cited
2006
Physical and functional interactions between MutY glycosylase homologue (MYH) and checkpoint proteins Rad9-Rad1-Hus1.
G. Shi
,
D. Chang
,
C. Cheng
,
Xin-min Guan
,
Č. Venclovas
,
A. Lu
Biochemical Journal
2006
Corpus ID: 16697328
The MYH (MutY glycosylase homologue) increases replication fidelity by removing adenines or 2-hydroxyadenine misincorporated…
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Review
2004
Review
2004
G2 checkpoint abrogators as anticancer drugs.
T. Kawabe
Molecular Cancer Therapeutics
2004
Corpus ID: 6190167
Many conventional anticancer treatments kill cells irrespective of whether they are normal or cancerous, so patients suffer from…
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Highly Cited
2004
Highly Cited
2004
Localization of hRad9, hHus1, hRad1, and hRad17 and Caffeine-sensitive DNA Replication at the Alternative Lengthening of Telomeres-associated Promyelocytic Leukemia Body*
A. Nabetani
,
Osamu Yokoyama
,
F. Ishikawa
Journal of Biological Chemistry
2004
Corpus ID: 8360797
Telomere maintenance is essential for continued cell proliferation. Although most cells accomplish this by activating telomerase…
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Review
2003
Review
2003
hRad9 rapidly binds DNA containing double-strand breaks and is required for damage-dependent topoisomerase II beta binding protein 1 focus formation.
D. A. Greer
,
Blair D. A. Besley
,
Katherine B. Kennedy
,
S. Davey
Cancer Research
2003
Corpus ID: 37790323
Checkpoint proteins protect the genomic integrity of a cell, repeatedly impaired by DNA damage and normal cellular processes…
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Highly Cited
2000
Highly Cited
2000
The Human Checkpoint Protein hRad17 Interacts with the PCNA-like Proteins hRad1, hHus1, and hRad9*
M. Rauen
,
M. Burtelow
,
Vanessa Dufault
,
L. Karnitz
Journal of Biological Chemistry
2000
Corpus ID: 34505615
DNA damage activates cell cycle checkpoints that prevent progression through the cell cycle. In yeast, the DNA damage checkpoint…
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Highly Cited
2000
Highly Cited
2000
Human DNA Damage Checkpoint Protein hRAD9 Is a 3′ to 5′ Exonuclease*
T. Bessho
,
A. Sancar
Journal of Biological Chemistry
2000
Corpus ID: 26851226
Human RAD9 protein (hRAD9) is a homolog of the fission yeast Rad9 protein, one of the six so-called checkpoint Rad proteins…
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Highly Cited
1999
Highly Cited
1999
Human Homologs of Schizosaccharomyces pombe Rad1, Hus1, and Rad9 Form a DNA Damage-responsive Protein Complex*
Elias Volkmer
,
L. Karnitz
Journal of Biological Chemistry
1999
Corpus ID: 28787137
DNA damage activates cell cycle checkpoints in yeast and human cells. In the yeasts Saccharomyces cerevisiae and…
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Highly Cited
1998
Highly Cited
1998
Identification of a Human Homologue of theSchizosaccharomyces pombe rad17 + Checkpoint Gene*
A. Parker
,
I. van de Weyer
,
Marc C. Laus
,
P. Verhasselt
,
W. Luyten
Journal of Biological Chemistry
1998
Corpus ID: 39076964
In the fission yeast Schizosaccharomyces pombe the rad17 + gene is required for both the DNA damage-dependent and the DNA…
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Highly Cited
1996
Highly Cited
1996
A human homolog of the Schizosaccharomyces pombe rad9+ checkpoint control gene.
H. Lieberman
,
K. M. Hopkins
,
Monica L. Nass
,
Douglas J. Demetrick
,
Scott Davey
Proceedings of the National Academy of Sciences…
1996
Corpus ID: 20066758
The product of the Schizosaccharomyces pombe rad9+ gene is required for cell cycle arrest at the G2 checkpoints in response to…
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