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RACGAP1 gene

Known as: MGCRACGAP, RAC GTPase-ACTIVATING PROTEIN 1, Rac GTPase activating protein 1 
National Institutes of Health

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Related topics

2 relations
RAN GTPase Activating Protein 1mgcRacGAP

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Formin-mediated epigenetic maintenance of centromere identity
ABSTRACT Accurate chromosome segregation in mammalian cells is guided by the centromere, a specialized chromosome region defined… 
2016
2016
Gene-expression Analysis Identifies Specific Patterns of Dysregulated Molecular Pathways and Genetic Subgroups of Human Hepatocellular Carcinoma.
BACKGROUND Hepatocellular carcinoma comprises of a group of heterogeneous tumors of different etiologies. The multistep process… 
2015
2015
Discovery of MINC1, a GTPase-Activating Protein Small Molecule Inhibitor, Targeting MgcRacGAP
The Rho family of Ras superfamily small GTPases regulates a broad range of biological processes such as migration… 
2014
2014
Identification of a mitotic Rac-GEF, Trio, that counteracts MgcRacGAP function during cytokinesis
Inactivation of Rac1 by MgcRacGAP at the cleavage plane is essential to ensure cytokinesis. Trio activates Rac1 in dividing cells… 
2013
2013
Aurora B but Not Rho/MLCK Signaling Is Required for Localization of Diphosphorylated Myosin II Regulatory Light Chain to the Midzone in Cytokinesis
Non-muscle myosin II is stimulated by monophosphorylation of its regulatory light chain (MRLC) at Ser19 (1P-MRLC). MRLC… 
2013
2013
Neuronal migration re-purposes mechanisms of cytokinesis
The capacity of cells to transition through the cell cycle is among the most complex and carefully orchestrated in biology, and… 
Highly Cited
2005
Highly Cited
2005
Aurora‐B and Rho‐kinase/ROCK, the two cleavage furrow kinases, independently regulate the progression of cytokinesis: possible existence of a novel cleavage furrow kinase phosphorylates ezrin/radixin…
Cytokinesis is regulated by several protein kinases, such as Aurora‐B and Rho‐kinase/ROCK. We have indicated that these two… 
2005
2005
Phosphorylation by Aurora B converts MgcRacGAP to a RhoGAP during cytokinesis
2002
2002
Role of MgcRacGAP / Cyk 4 as a Regulator of the Small GTPase Rho Family in Cytokinesis and Cell Differentiation
To identify the key molecules that regulate differentiation of hematopoietic cells, we carried out retrovirus-mediated functional… 
2001
2001
Role of MgcRacGAP/Cyk4 as a regulator of the small GTPase Rho family in cytokinesis and cell differentiation.
To identify the key molecules that regulate differentiation of hematopoietic cells, we carried out retrovirus-mediated functional… 
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