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RABGEF1 gene

Known as: rabex-5, RAB GUANINE NUCLEOTIDE EXCHANGE FACTOR 1, RABGEF1 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
A fresh look at the function of Rabaptin5 on endosomes
ABSTRACT Rab GTPases act as organizers of protein networks defining identities and functions of organelles of the endocytic and… 
2016
2016
Epithelial Rab guanine nucleotide exchange factor 1 (Rabgef1) deficiency increases susceptibility to DSS-induced intestinal inflammation in mice
2015
2015
Assay of Rab17 and its guanine nucleotide exchange factor Rabex-5 in the dendrites of hippocampal neurons.
Neurons are functionally and morphologically compartmentalized into axons and dendrites, and the localization of specific… 
2014
2014
Expression of RABEX-5 and its clinical significance in prostate cancer
While recent research has shown that expression of RABEX-5 in breast cancer and colorectal cancer has a crucial impact on tumor… 
2013
2013
Rabex-5 determines the neurite localization of its downstream Rab proteins in hippocampal neurons
Rab family small GTPases function as molecular switches in the regulation of membrane traffic, and their activity is thought to… 
2013
2013
[The effect of RABEX-5 downregulation on the chemosensitivity of human breast cancer cells].
OBJECTIVE To investigate the changes in sensitivity to anthracycline and taxanes of human breast cancer cells after RABEX-5… 
2013
2013
Rabex-5 Regulates Dendritic Localization of Rab 17 and Neurite Morphogenesis in Hippocampal Neurons *
Background: Small GTPase Rab17 regulates dendritic morphogenesis of hippocampal neurons, but its activation mechanism is… 
2011
2011
[The expression and clinical significance of RABEX-5 and RAB5 in breast cancer].
OBJECTIVE To study the expression and significance of RABEX-5 and RAB5 in human breast cancer. METHODS In this study the… 
2010
2010
Delayed Onset of Positive Feedback Activation of Rab5 by Rabex-5 and Rabaptin-5 in Endocytosis
Background Rabex-5 is a guanine nucleotide exchange factor (GEF) that specifically activates Rab5, i.e., converting Rab5-GDP to… 
2005
2005
The Rab 5 Guanine Nucleotide Exchange Factor Rabex-5 Binds Ubiquitin and Functions as a Ubiquitin Ligase through an Atypical UIM and a Zinc Finger Domain
Rabex-5, the mammalian orthologue of yeast Vps9p, is a guanine nucleotide exchange factor for Rab5. Rabex-5 forms a tight complex… 
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