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QX-314

Known as: 2-((2,6-dimethylphenyl)amino)-N,N,N-triethyl-2-oxoethanaminium, QX 314 
 
National Institutes of Health

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Highly Cited
2009
Highly Cited
2009
BACKGROUND Nociceptive-selective local anesthesia is produced by entry of the permanently charged lidocaine-derivative QX-314… Expand
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Highly Cited
2007
Highly Cited
2007
Most local anaesthetics used clinically are relatively hydrophobic molecules that gain access to their blocking site on the… Expand
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2006
2006
Seminal work by Weitzman [Prices vs. quantities, Rev. Econ. Stud. 41 (1974) 477–491] revealed prices are preferred to quantities… Expand
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1997
1997
In animal models of neuropathic pain, transection or constrictive injury to peripheral nerves produces ectopic discharges… Expand
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Highly Cited
1995
Highly Cited
1995
1. Whole cell voltage-clamp recordings (access resistance < or = 12 M omega) from CA1 pyramidal cells in the guinea pig… Expand
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Highly Cited
1991
Highly Cited
1991
Horizontal connections are a principal component of intrinsic cortical circuitry. They arise mainly from pyramidal cells and… Expand
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Highly Cited
1990
Highly Cited
1990
Intracellular recordings were made from CA1 pyramidal neurones in the rat hippocampus slice preparation. The recording electrodes… Expand
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Highly Cited
1982
Highly Cited
1982
The quaternary lidocaine derivative QX-314 was applied internally to CA1 pyramidal neurons of the guinea-pig hippocampal slice… Expand
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Highly Cited
1978
Highly Cited
1978
1. Single channel currents through acetylcholine receptor channels (ACh channels) were recorded at chronically denervated frog… Expand
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1978
1978
  • Jay Z. Yeh
  • Biophysical journal
  • 1978
  • Corpus ID: 26398587
Blocking action of Na channels by QX-314, a quaternary derivative of lidocaine, was studied in internally perfused and voltage… Expand
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