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Pyruvate Dehydrogenase Complex

Known as: Complex, Pyruvate Dehydrogenase, Dehydrogenase Complex, Pyruvate, Pyruvate Dehydrogenase Complex [Chemical/Ingredient] 
A multienzyme complex responsible for the formation of ACETYL COENZYME A from pyruvate. The enzyme components are PYRUVATE DEHYDROGENASE (LIPOAMIDE… Expand
National Institutes of Health

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Highly Cited
2008
Highly Cited
2008
High lactate generation and low glucose oxidation, despite normal oxygen conditions, are commonly seen in cancer cells and tumors… Expand
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Review
2003
Review
2003
PDC (pyruvate dehydrogenase complex) catalyses the oxidative decarboxylation of pyruvate, linking glycolysis to the tricarboxylic… Expand
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Highly Cited
2003
Highly Cited
2003
The pyruvate dehydrogenase complex (PDC) is subjected to multiple interacting levels of control in plant cells. The first level… Expand
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Highly Cited
2002
Highly Cited
2002
Pyruvate dehydrogenase kinase (PDK) catalyzes phosphorylation and inactivation of the pyruvate dehydrogenase complex (PDC). Two… Expand
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Highly Cited
1999
Highly Cited
1999
Regulation of the activity of the pyruvate dehydrogenase complex in skeletal muscle plays an important role in fuel selection and… Expand
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Highly Cited
1998
Highly Cited
1998
Tissue distribution and kinetic parameters for the four isoenzymes of pyruvate dehydrogenase kinase (PDK1, PDK2, PDK3 and PDK4… Expand
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Highly Cited
1998
Highly Cited
1998
This study investigated whether conditions known to alter the activity and phosphorylation state of the pyruvate dehydrogenase… Expand
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Review
1990
Review
1990
  • M. Patel, T. Roche
  • FASEB journal : official publication of the…
  • 1990
  • Corpus ID: 8112416
In most organisms, the pyruvate dehydrogenase complex catalyzes the pivotal irreversible reaction that leads to the consumption… Expand
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Highly Cited
1983
Highly Cited
1983
The activity of the pyruvate dehydrogenase complex (PDHC) was reduced in affected areas of brain from patients with Huntington… Expand
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Highly Cited
1969
Highly Cited
1969
This paper reports the discovery that the activity of the multienzyme pyruvate dehydrogenase complex from beef kidney… Expand
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