Pyruvate Dehydrogenase Complex

Known as: Complex, Pyruvate Dehydrogenase, Dehydrogenase Complex, Pyruvate, Pyruvate Dehydrogenase Complex [Chemical/Ingredient] 
A multienzyme complex responsible for the formation of ACETYL COENZYME A from pyruvate. The enzyme components are PYRUVATE DEHYDROGENASE (LIPOAMIDE… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1964-2017
0204019642017

Papers overview

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Highly Cited
2008
Highly Cited
2008
High lactate generation and low glucose oxidation, despite normal oxygen conditions, are commonly seen in cancer cells and tumors… (More)
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Highly Cited
2003
Highly Cited
2003
The pyruvate dehydrogenase complex (PDC) is subjected to multiple interacting levels of control in plant cells. The first level… (More)
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Highly Cited
2002
Highly Cited
2002
Pyruvate dehydrogenase kinase (PDK) catalyzes phosphorylation and inactivation of the pyruvate dehydrogenase complex (PDC). Two… (More)
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Highly Cited
1999
Highly Cited
1999
Regulation of the activity of the pyruvate dehydrogenase complex in skeletal muscle plays an important role in fuel selection and… (More)
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Highly Cited
1998
Highly Cited
1998
Tissue distribution and kinetic parameters for the four isoenzymes of pyruvate dehydrogenase kinase (PDK1, PDK2, PDK3 and PDK4… (More)
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Highly Cited
1998
Highly Cited
1998
This study investigated whether conditions known to alter the activity and phosphorylation state of the pyruvate dehydrogenase… (More)
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Highly Cited
1995
Highly Cited
1995
We established six T cell clones specific for pyruvate dehydrogenase complex (PDC)-E2 peptides from four different patients with… (More)
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Highly Cited
1991
Highly Cited
1991
A radioactive assay for the determination of pyruvate dehydrogenase complex activity in muscle tissue has been developed. The… (More)
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Highly Cited
1983
Highly Cited
1983
The activity of the pyruvate dehydrogenase complex (PDHC) was reduced in affected areas of brain from patients with Huntington… (More)
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Highly Cited
1969
Highly Cited
1969
This paper reports the discovery that the activity of the multienzyme pyruvate dehydrogenase complex from beef kidney… (More)
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