Pyrogens

Known as: Pyrogen 
Substances capable of increasing BODY TEMPERATURE and cause FEVER and may be used for FEVER THERAPY. They may be of microbial origin, often… (More)
National Institutes of Health

Papers overview

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Review
2010
Review
2010
The inefficient clearance of dying cells can result in the accumulation of apoptotic cell remnants. This occurrence is considered… (More)
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Review
2009
Review
2009
Inflammation can cause damage and even death. What controls this primitive and potentially lethal innate immune response to… (More)
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Review
2004
Review
2004
For many years, it was thought that bacterial products caused fever via the intermediate production of a host-derived, fever… (More)
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Review
2000
Review
2000
Lesion and thermal stimulation studies suggest that temperature regulation is controlled by a hierarchy of neural structures… (More)
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Review
1998
Review
1998
In humans or experimental animals, the repeated confrontation with lipopolysaccharides (LPS) from gram-negative bacteria, but not… (More)
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1995
1995
The use of human whole blood as an in vitro model for detection of compounds with the potential to induce fever is described. As… (More)
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Highly Cited
1986
Highly Cited
1986
Recombinant human tumor necrosis factor (rTNF alpha) injected intravenously into rabbits produces a rapid-onset, monophasic fever… (More)
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Highly Cited
1984
Highly Cited
1984
When infused into the lateral cerebral ventricles of rabbits, human endogenous pyrogen (EP) preparations induced dose-dependent… (More)
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1974
1974
Human monocytes and neutrophils were separated from buffy coats of blood obtained from normal donors. Following incubation with… (More)
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Highly Cited
1947
Highly Cited
1947
In a study of the febrile responses of rabbits to repeated intravenous injections of pyrogenic substances from Eberthella typhosa… (More)
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