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Pyridoxamine

Known as: 3-Pyridinemethanol, 4-(aminomethyl)-5-hydroxy-6-methyl-, Pyridoxamine [Chemical/Ingredient] 
The 4-aminomethyl form of VITAMIN B 6. During transamination of amino acids, PYRIDOXAL PHOSPHATE is transiently converted into pyridoxamine phosphate… 
National Institutes of Health

Related topics

Related topics

18 relations
In BloodProcess of secretionPyridoxal PhosphateVitamin B6
Expand

Broader (2)

PicolineVitamin B Complex

Narrower (4)

bromoacetylpyridoxaminebromoacetylpyridoxamine phosphatepyridoxamine dihydrochloridepyridoxamine phosphate

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
Diabetic cardiomyopathy: understanding the molecular and cellular basis to progress in diagnosis and treatment
Diabetes mellitus is an important and prevalent risk factor for congestive heart failure. Diabetic cardiomyopathy has been… 
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Review
2009
Review
2009
Hyperglycemia and glycation in diabetic complications.
Diabetes mellitus is a multifactorial disease, classically influenced by genetic determinants of individual susceptibility and by… 
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Highly Cited
2007
Highly Cited
2007
Effects of Pyridoxamine in Combined Phase 2 Studies of Patients with Type 1 and Type 2 Diabetes and Overt Nephropathy
Background/Aims: Treatments of diabetic nephropathy (DN) delay the onset of end-stage renal disease. We report the results of… 
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Review
2006
Review
2006
Protein carbonylation, cellular dysfunction, and disease progression
Carbonylation of proteins is an irreversible oxidative damage, often leading to a loss of protein function, which is considered a… 
Review
2005
Review
2005
Pyridoxamine as a multifunctional pharmaceutical: targeting pathogenic glycation and oxidative damage
Abstract.The discovery that pyridoxamine (PM) can inhibit glycation reactions and the formation of advanced glycation end… 
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Review
2004
Review
2004
Protein Glycation: A Firm Link to Endothelial Cell Dysfunction
The advanced glycation end products (AGEs) are a heterogeneous class of molecules, including the following main subgroups: bis… 
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Highly Cited
2002
Highly Cited
2002
Pyridoxamine inhibits early renal disease and dyslipidemia in the streptozotocin-diabetic rat.
BACKGROUND Nonenzymatic reactions between sugars or lipids and protein and formation of advanced glycation and lipoxidation end… 
Highly Cited
2002
Highly Cited
2002
The AGE inhibitor pyridoxamine inhibits development of retinopathy in experimental diabetes.
We examined the ability of pyridoxamine (PM), an inhibitor of formation of advanced glycation end products (AGEs) and… 
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Highly Cited
2002
Highly Cited
2002
Effect of pyridoxamine on chemical modification of proteins by carbonyls in diabetic rats: characterization of a major product from the reaction of pyridoxamine and methylglyoxal.
Advanced glycation end products (AGEs) from the Maillard reaction contribute to protein aging and the pathogenesis of age- and… 
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Highly Cited
1961
Highly Cited
1961
The enzymatic oxidation of pyridoxine and pyridoxamine phosphates.
Extracts of rabbit liver and brain are known (1, 2) to oxidize pyridoxine 5-phosphate to pyridoxal 5-phosphate much faster than… 
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