Pyridoxamine

Known as: 3-Pyridinemethanol, 4-(aminomethyl)-5-hydroxy-6-methyl-, Pyridoxamine [Chemical/Ingredient] 
The 4-aminomethyl form of VITAMIN B 6. During transamination of amino acids, PYRIDOXAL PHOSPHATE is transiently converted into pyridoxamine phosphate… (More)
National Institutes of Health

Related topics

Related topics

18 relations
In BloodProcess of secretionPyridoxal PhosphateVitamin B6
(More)

Broader (2)

PicolineVitamin B Complex

Narrower (4)

bromoacetylpyridoxaminebromoacetylpyridoxamine phosphatepyridoxamine dihydrochloridepyridoxamine phosphate

Papers overview

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Review
2006
Review
2006
Protein carbonylation, cellular dysfunction, and disease progression
Carbonylation of proteins is an irreversible oxidative damage, often leading to a loss of protein function, which is considered a… (More)
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Highly Cited
2006
Highly Cited
2006
Role of collagen enzymatic and glycation induced cross-links as a determinant of bone quality in spontaneously diabetic WBN/Kob rats
Diabetes is associated with an increased risk of fracture, although type 2 diabetes is often characterized by normal bone mineral… (More)
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Review
2005
Review
2005
Pyridoxamine: the many virtues of a maillard reaction inhibitor.
Pyridoxamine (PM) is one of three natural forms of vitamin B6. It is a critical transient intermediate in catalysis of… (More)
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Review
2005
Review
2005
Pyridoxamine as a multifunctional pharmaceutical: targeting pathogenic glycation and oxidative damage
The discovery that pyridoxamine (PM) can inhibit glycation reactions and the formation of advanced glycation end products (AGEs… (More)
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Highly Cited
2002
Highly Cited
2002
Pyridoxamine inhibits early renal disease and dyslipidemia in the streptozotocin-diabetic rat.
BACKGROUND Nonenzymatic reactions between sugars or lipids and protein and formation of advanced glycation and lipoxidation end… (More)
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Highly Cited
2002
Highly Cited
2002
The AGE inhibitor pyridoxamine inhibits development of retinopathy in experimental diabetes.
We examined the ability of pyridoxamine (PM), an inhibitor of formation of advanced glycation end products (AGEs) and… (More)
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Highly Cited
2002
Highly Cited
2002
Effect of pyridoxamine on chemical modification of proteins by carbonyls in diabetic rats: characterization of a major product from the reaction of pyridoxamine and methylglyoxal.
Advanced glycation end products (AGEs) from the Maillard reaction contribute to protein aging and the pathogenesis of age- and… (More)
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Highly Cited
2001
Highly Cited
2001
Pyridoxine and pyridoxamine inhibits superoxide radicals and prevents lipid peroxidation, protein glycosylation, and (Na+ + K+)-ATPase activity reduction in high glucose-treated human erythrocytes.
Vitamin B(6) (pyridoxine) supplementation has been found beneficial in preventing diabetic neuropathy and retinopathy, and the… (More)
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Highly Cited
2000
Highly Cited
2000
Pyridoxamine, an inhibitor of advanced glycation reactions, also inhibits advanced lipoxidation reactions. Mechanism of action of pyridoxamine.
Maillard or browning reactions lead to formation of advanced glycation end products (AGEs) on protein and contribute to the… (More)
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1961
1961
The enzymatic oxidation of pyridoxine and pyridoxamine phosphates.
Extracts of rabbit liver and brain are known (1, 2) to oxidize pyridoxine 5-phosphate to pyridoxal 5-phosphate much faster than… (More)
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