Pyridoxal Phosphate

Known as: Pyridoxal Phosphate [Chemical/Ingredient], 4-Pyridinecarboxaldehyde, 3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-, 3-hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde 5-phosphate 
The active form of vitamin B6 and a coenzyme for many pyridoxal phosphate (PLP)-dependent enzymes. PLP is involved in numerous enzymatic… (More)
National Institutes of Health

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Narrower (20)

4-deoxypyridoxine 5'-phosphate6-fluoropyridoxal phosphateMRS 2211MRS2159
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Broader (4)

CoenzymesPyridoxalVitamin B Complexchemical cofactor
Drug AllergyDrug toxicityIn BloodProcess of secretion
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Papers overview

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Review
2017
Review
2017
Hypophosphatasia: An overview For 2017.
Hypophosphatasia (HPP) is the inborn-error-of-metabolism that features low serum alkaline phosphatase (ALP) activity… (More)
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Highly Cited
2005
Highly Cited
2005
Neonatal epileptic encephalopathy caused by mutations in the PNPO gene encoding pyridox(am)ine 5'-phosphate oxidase.
In the mouse, neurotransmitter metabolism can be regulated by modulation of the synthesis of pyridoxal 5'-phosphate and failure… (More)
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Review
2005
Review
2005
Reaction specificity in pyridoxal phosphate enzymes.
Pyridoxal phosphate enzymes catalyze a wide variety of reaction types on amines and amino acids, generally by stabilizing… (More)
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Review
2003
Review
2003
Pyridoxal phosphate enzymes: mechanistic, structural, and evolutionary considerations.
Pyridoxal phosphate (PLP)-dependent enzymes are unrivaled in the diversity of reactions that they catalyze. New structural data… (More)
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Highly Cited
2001
Highly Cited
2001
Structure of human cystathionine beta-synthase: a unique pyridoxal 5'-phosphate-dependent heme protein.
Cystathionine beta-synthase (CBS) is a unique heme- containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent… (More)
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Highly Cited
2000
Highly Cited
2000
Measurement of plasma and intracellular S-adenosylmethionine and S-adenosylhomocysteine utilizing coulometric electrochemical detection: alterations with plasma homocysteine and pyridoxal 5…
BACKGROUND The relative changes in plasma and intracellular concentrations of S-adenosylmethionine (SAM) and S… (More)
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Highly Cited
1995
Highly Cited
1995
Hyperhomocysteinemia and low pyridoxal phosphate. Common and independent reversible risk factors for coronary artery disease.
BACKGROUND High plasma homocysteine is associated with premature coronary artery disease in men, but the threshold concentration… (More)
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Highly Cited
1995
Highly Cited
1995
Homocysteine and coronary artery disease in French Canadian subjects: relation with vitamins B12, B6, pyridoxal phosphate, and folate.
We determined plasma levels of homocysteine in 584 healthy subjects (380 men and 204 women) from a major utility company in the… (More)
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Highly Cited
1991
Highly Cited
1991
Two genes encode distinct glutamate decarboxylases
gamma-Aminobutyric acid (GABA) is the most widely distributed known inhibitory neurotransmitter in the vertebrate brain. GABA… (More)
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Highly Cited
1979
Highly Cited
1979
Ethylene biosynthesis: Identification of 1-aminocyclopropane-1-carboxylic acid as an intermediate in the conversion of methionine to ethylene.
L-[U-(14)C]Methionine fed to apple tissue was efficiently converted to ethylene when the tissue was incubated in air. In nitrogen… (More)
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