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Pyridoxal Phosphate

Known as: Pyridoxal Phosphate [Chemical/Ingredient], 4-Pyridinecarboxaldehyde, 3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-, 3-hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde 5-phosphate 
The active form of vitamin B6 and a coenzyme for many pyridoxal phosphate (PLP)-dependent enzymes. PLP is involved in numerous enzymatic… Expand
National Institutes of Health

Related topics

Related topics

43 relations

Narrower (20)

4-deoxypyridoxine 5'-phosphate6-fluoropyridoxal phosphateMRS 2211MRS2159
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Broader (4)

CoenzymesPyridoxalVitamin B Complexchemical cofactor
Drug AllergyDrug toxicityIn BloodProcess of secretion
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
Pyridoxine-Dependent Epilepsy: An Expanding Clinical Spectrum.
BACKGROUND Pyridoxine-dependent epilepsy is a rare autosomal recessive epileptic encephalopathy caused by antiquitin (ALDH7A1… Expand
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Highly Cited
2007
Highly Cited
2007
Olig2-Regulated Lineage-Restricted Pathway Controls Replication Competence in Neural Stem Cells and Malignant Glioma
Recent studies have identified stem cells in brain cancer. However, their relationship to normal CNS progenitors, including… Expand
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Review
2005
Review
2005
Reaction specificity in pyridoxal phosphate enzymes.
  • M. Toney
  • Archives of biochemistry and biophysics
  • 2005
    • Corpus ID: 28577743
Pyridoxal phosphate enzymes catalyze a wide variety of reaction types on amines and amino acids, generally by stabilizing… Expand
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Review
2004
Review
2004
Pyridoxal phosphate enzymes: mechanistic, structural, and evolutionary considerations.
Pyridoxal phosphate (PLP)-dependent enzymes are unrivaled in the diversity of reactions that they catalyze. New structural data… Expand
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Review
2004
Review
2004
Determination of the Core of a Minimal Bacterial Gene Set
SUMMARY The availability of a large number of complete genome sequences raises the question of how many genes are essential for… Expand
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Highly Cited
2001
Highly Cited
2001
Structure of human cystathionine β‐synthase: a unique pyridoxal 5′‐phosphate‐dependent heme protein
Cystathionine β‐synthase (CBS) is a unique heme‐ containing enzyme that catalyzes a pyridoxal 5′‐phosphate (PLP)‐dependent… Expand
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Highly Cited
1997
Highly Cited
1997
Plasma homocysteine as a risk factor for vascular disease. The European Concerted Action Project.
CONTEXT Elevated plasma homocysteine is a known risk factor for atherosclerotic vascular disease, but the strength of the… Expand
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Highly Cited
1995
Highly Cited
1995
Hyperhomocysteinemia and low pyridoxal phosphate. Common and independent reversible risk factors for coronary artery disease.
BACKGROUND High plasma homocysteine is associated with premature coronary artery disease in men, but the threshold concentration… Expand
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Highly Cited
1991
Highly Cited
1991
Two genes encode distinct glutamate decarboxylases
gamma-Aminobutyric acid (GABA) is the most widely distributed known inhibitory neurotransmitter in the vertebrate brain. GABA… Expand
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Highly Cited
1979
Highly Cited
1979
Ethylene biosynthesis: Identification of 1-aminocyclopropane-1-carboxylic acid as an intermediate in the conversion of methionine to ethylene.
  • D. O. Adams, S. Yang
  • Proceedings of the National Academy of Sciences…
  • 1979
    • Corpus ID: 24218991
L-[U-(14)C]Methionine fed to apple tissue was efficiently converted to ethylene when the tissue was incubated in air. In nitrogen… Expand
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