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Puromycin

Known as: Adenosine, 3'-(alpha-amino-p-methoxyhydrocinnamamido)-3'-deoxy-N,N-dimethyl-, L-, Puromycinum, L-3'-(alpha-Amino-p-methoxyhydrocinnamamido)-3'-deoxy-N,N-dimethyladenosine 
An aminoglycoside antibiotic isolated from the bacterium Streptomyces alboniger. Acting as an analog of the 3' terminal end of aminoacyl-tRNA… 
National Institutes of Health

Related topics

Related topics

32 relations

Narrower (15)

2'-deoxy-2'-fluoropuromycin2'-deoxypuromycin4-azidopuromycinCCdApPuro

Broader (8)

AminesAntibioticsAntibiotics, AntineoplasticAntimetabolites, Antineoplastic
In BloodNCIt Antineoplastic Agent TerminologyPuromycin Hydrochlorideagonists

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Nuclear translation visualized by ribosome-bound nascent chain puromycylation
A new method for visualizing translation in cells via standard immunofluorescence microscopy provides evidence for translation in… 
Highly Cited
2005
Highly Cited
2005
Puromycin‐based purification of rat brain capillary endothelial cell cultures. Effect on the expression of blood–brain barrier‐specific properties
One of the main difficulties with primary rat brain endothelial cell (RBEC) cultures is obtaining pure cultures. The variation in… 
Review
2004
Review
2004
In-vitro protein evolution by ribosome display and mRNA display.
Highly Cited
1983
Highly Cited
1983
The enkephalins are amongst the peptides hydrolyzed by purified acetylcholinesterase
Highly Cited
1980
Highly Cited
1980
Cultured animal cells exposed to amino acid analogues or puromycin rapidly synthesize several polypeptides
  • L. Hightower
  • Journal of cellular physiology
  • 1980
  • Corpus ID: 24608881
Four major acidic polypeptides, with molecular weights of 88, 72, 71, and 23 thousand, and minor polypeptides with molecular… 
Highly Cited
1967
Highly Cited
1967
Bacterial protein synthesis: the effects of antibiotics.
Highly Cited
1966
Highly Cited
1966
Requirement for RNA and protein synthesis for induced regression of the tadpole tail in organ culture.
  • J. Tata
  • Developmental biology
  • 1966
  • Corpus ID: 46061497
Highly Cited
1966
Highly Cited
1966
Chemical studies on memory fixation in goldfish.
Highly Cited
1966
Highly Cited
1966
Ribonucleic acid synthesis during the early action of thyroid hormones.
1. The effect on RNA synthesis in rat liver of thyroidectomy and the administration of thyroid hormone, especially during its… 
Highly Cited
1963
Highly Cited
1963
Polypeptide synthesis in Escherichia coli. II. The polypeptide chain and S-RNA.
  • W. Gilbert
  • Journal of molecular biology
  • 1963
  • Corpus ID: 38750479
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