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Puromycin

Known as: Adenosine, 3'-(alpha-amino-p-methoxyhydrocinnamamido)-3'-deoxy-N,N-dimethyl-, L-, Puromycinum, L-3'-(alpha-Amino-p-methoxyhydrocinnamamido)-3'-deoxy-N,N-dimethyladenosine 
An aminoglycoside antibiotic isolated from the bacterium Streptomyces alboniger. Acting as an analog of the 3' terminal end of aminoacyl-tRNA… 
National Institutes of Health

Related topics

Related topics

32 relations

Narrower (15)

2'-deoxy-2'-fluoropuromycin2'-deoxypuromycin4-azidopuromycinCCdApPuro

Broader (8)

AminesAntibioticsAntibiotics, AntineoplasticAntimetabolites, Antineoplastic
In BloodNCIt Antineoplastic Agent TerminologyPuromycin Hydrochlorideagonists

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1979
1979
The mechanism of decrease in nucleolar RNA synthesis by protein synthesis inhibition.
When protein biosynthesis is inhibited by either cycloheximide of puromycine, the nucleolar RNA synthesis of Ehrlich ascites… 
1978
1978
Effect of sparsomycin analogues on the puromycin-peptidyl transferase reaction on ribosomes.
Sparsomycin analogues in which the unique -S(O)CH2SCH3 moiety was replaced by a variety of more easily accessible side chains… 
1977
1977
N-methylated tetraphenylporphins.
Methylation of meso-tetraphenylporphin affords N-methyl, trans-NaNb-dimethyl, and trans,trans-NaNbNc-trimethyl derivatives. The… 
Highly Cited
1972
Highly Cited
1972
Specific inhibition of peptide-chain initiation by 2-(4-methyl-2,6-dinitroanilino)-N-methylpropionamide.
M DMP (2-(4-methyl-2,6-dinitroanilino)-N-methyl- propionamide) is a potent inhibitor of mRNA-dependent amino acid incorporation… 
1967
1967
The Reticuloendothelial System and Atherosclerosis
A mathematical model of RES phagocytic function has been developed. Data obtained using this model are compatible with results… 
Highly Cited
1965
Highly Cited
1965
EXTRACELLULAR RIBONUCLEASE FORMATION IN BACILLUS SUBTILIS AND ITS STIMULATION BY ACTINOMYCIN D.
1. Extracellular ribonuclease is produced linearly for at least 3hr. by washed post-logarithmic-phase cells of Bacillus subtilis… 
1964
1964
Selective Toxicity of Mikamycins, Inhibitors of Protein Synthesis
MIKAMYCIN, an antibiotic belonging to the group of PA114, streptogramin, staphylomycin and ostreogrycin, is composed of two main… 
Highly Cited
1963
Highly Cited
1963
Action of Insulin on the Isolated Rat Diaphragm in the Presence of Actinomycin D and Puromycin
WITHIN recent years, conclusive evidence has been obtained of a direct stimulation of transport of sugar from the extracellular… 
1963
1963
EFFECTS OF PUROMYCIN ON RNA SYNTHESIS IN MAMMALIAN CELLS.
Puromycin is a potent inhibitor of protein synthesis both in vitro and in vivo.1, 2 In addition, it is known to inhibit RNA… 
1963
1963
Effect of Puromycin on Cholinesterase Activity of Embryonic Chick Intestine in Organ Culture
THE acetylcholinesterase (AChE) activity of a number of chick embryo tissues cultured in vitro can be influenced by the presence… 
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