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Purine Nucleoside Phosphorylase, human

Known as: PNP Human, Purine Nucleoside Phosphorylase, NP 
Purine nucleoside phosphorylase (289 aa, ~32 kDa) is encoded by the human PNP gene. This protein plays a role in purine metabolism.
National Institutes of Health

Related topics

Related topics

9 relations
Carbohydrate MetabolismEnzyme GeneGlycosyltransferase GeneNucleotide Metabolism

Broader (1)

Purine-Nucleoside Phosphorylase

Papers overview

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1994
1994
Background conductance attributable to spontaneous opening of muscarinic K+ channels in rabbit sino‐atrial node cells.
Single myocytes were dissociated from the rabbit sino‐atrial node, and the membrane background conductance produced by… 
Highly Cited
1990
Highly Cited
1990
Purine salvage enzyme activities in normal and neoplastic human tissues.
The enzymatic pattern of five enzymes involved in the purine salvage pathway, namely purine nucleoside phosphorylase (EC 2.4.2.1… 
1988
1988
Design of vectors for efficient expression of human purine nucleoside phosphorylase in skin fibroblasts from enzyme-deficient humans.
Purine nucleoside phosphorylase (PNP; purine-nucleoside orthophosphate ribosyltransferase, EC 2.4.2.1) deficiency is an inherited… 
Highly Cited
1986
Highly Cited
1986
Properties of two unusual, and fluorescent, substrates of purine-nucleoside phosphorylase: 7-methylguanosine and 7-methylinosine.
Highly Cited
1979
Highly Cited
1979
Selective toxicity of purine deoxynucleosides for human lymphocyte growth and function.
A role for the enzymes adenosine deaminase (adenosine aminohydrolase, EC 3.5.4.4) and purine-nucleoside phosphorylase (purine… 
1979
1979
Purine salvage in cotyledons of germinating lupin seeds
1976
1976
Chinese hamster purine-nucleoside phosphorylase: purification, structural, and catalytic properties.
Purine-nucleoside phosphorylase (EC 2.4.2.1; purine-nucleosideorthophosphate ribosyltransferase) was purified to apparent… 
1976
1976
Monomeric purine nucleoside phosphorylase from rabbit liver. Purification and characterization.
1972
1972
Changes in sarcoma 180 cells associated with drug-induced resistance to adenosine analogs.
Summary A subline of mouse Sarcoma 180 (S-180) cells, resistant to adenosine analogs, was selected in cell culture by serial… 
1970
1970
Metabolic interlock. The influence of histidine on tryptophan biosynthesis in Bacillus subtilis.
Abstract A regulatory relationship in Bacillus subtilis between histidine and the synthesis of tryptophan exemplifies "metabolic… 
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