Purine Nucleoside Phosphorylase, human

Known as: PNP Human, Purine Nucleoside Phosphorylase, NP 
Purine nucleoside phosphorylase (289 aa, ~32 kDa) is encoded by the human PNP gene. This protein plays a role in purine metabolism.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Here we define the molecular nature of the mitochondrial permeability transition pore (PTP), a key effector of cell death. The… (More)
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Highly Cited
2012
Highly Cited
2012
Cerium dioxide nanoparticles (CeO(2) NPs) have diversified industrial uses, and novel therapeutic applications are actively being… (More)
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Highly Cited
2010
Highly Cited
2010
Curcumin, a yellow pigment present in the spice turmeric (Curcuma longa), has been linked with antioxidant, anti-inflammatory… (More)
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Highly Cited
2008
Highly Cited
2008
Purpose of the present work was to study in vitro permeation of gold nanoparticles (NPs) through isolated rat skin and intestine… (More)
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2005
2005
Human purine nucleoside phosphorylase has been submitted to intensive structure-based design of inhibitors, most of them using… (More)
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Highly Cited
1994
Highly Cited
1994
The ability of beta cells to endure assaults may be relevant in the development of insulin-dependent diabetes mellitus. This… (More)
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Highly Cited
1992
Highly Cited
1992
  • Martin R Webb
  • Proceedings of the National Academy of Sciences…
  • 1992
A spectrophotometric method for the measurement of inorganic phosphate (P(i)) has been developed by using 2-amino-6-mercapto-7… (More)
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1991
1991
Competitive inhibitors of the salvage pathway enzyme purine-nucleoside phosphorylase (purine-nucleoside:orthophosphate… (More)
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1991
1991
Purine nucleoside phosphorylase (EC 2.4.2.1) from bovine spleen is a trimeric enzyme that readily dissociates to the monomer… (More)
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Highly Cited
1977
Highly Cited
1977
Inherited deficiencies of the enzymes adenosine deaminase (adenosine aminohydrolase; EC 3.5.4.4) and purine nucleoside… (More)
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