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Purine Nucleoside Phosphorylase, human

Known as: PNP Human, Purine Nucleoside Phosphorylase, NP 
Purine nucleoside phosphorylase (289 aa, ~32 kDa) is encoded by the human PNP gene. This protein plays a role in purine metabolism.
National Institutes of Health

Related topics

Related topics

9 relations
Carbohydrate MetabolismEnzyme GeneGlycosyltransferase GeneNucleotide Metabolism

Broader (1)

Purine-Nucleoside Phosphorylase

Papers overview

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1984
1984
Biochemical studies on the purine metabolism of four cases with hereditary xanthinuria.
The purine metabolism of four cases with marked hypouricemia (serum uric acid concentration of less than 0.018 mmol/l) from three… 
1983
1983
The metabolism of deoxyguanosine and guanosine in human B and T lymphoblasts. A role for deoxyguanosine kinase activity in the selective T-cell defect associated with purine nucleoside phosphorylase…
Purine nucleoside phosphorylase (NP; EC 2.4.2.1) deficiency is associated with defective T-cell and normal B-cell immunity… 
1979
1979
Purine nucleoside phosphorylase cleaves the C--O bond of ribose 1-phosphate. Evidence from the 18O shift in 31P NMR.
An equilibrium mixture of highly enriched [18(O)]Pi (represents the mixture of [[18(O)4]Pi, [[18(O)3]Pi, [18(O)2]Pi as… 
1978
1978
Differences in purine metabolizing enzyme activities in human leukemia T-cell, B-cell and null cell lines.
Clear metabolic differences between T- and B-cells were demonstrated. Both adenosine deaminase (ADA) and nucleoside phosphorylase… 
1978
1978
Purification and some properties of a neutral muscle pyrophosphatase.
In the water-soluble fraction of rabbit skeletal muscle, at least two types of inorganic pyro phosphatase (PPase) are… 
1978
1978
Characterisation of purine nucleoside phosphorylase from fibroblasts using ultra-microchemical methods.
A new technique to quantitate nucleoside phosphorylase (NP) activity in single or small numbers of counted visually selected… 
1976
1976
Chinese hamster purine-nucleoside phosphorylase: purification, structural, and catalytic properties.
Purine-nucleoside phosphorylase (EC 2.4.2.1; purine-nucleosideorthophosphate ribosyltransferase) was purified to apparent… 
1975
1975
Guanosine metabolism and regulation of fruiting body construction in dictyostelium discoideum.
A cell aggregate of Dictyostelium discoideum either constructs a fruiting body directly or transforms into a migrating slug and… 
1970
1970
Metabolic interlock. The influence of histidine on tryptophan biosynthesis in Bacillus subtilis.
Abstract A regulatory relationship in Bacillus subtilis between histidine and the synthesis of tryptophan exemplifies "metabolic… 
1967
1967
Studies on mutant phenylalanyl RNA synthetases of Escherichia coli.
The temperature conditional mutant NP 37 of Escherichia coli differs from the wild type K 10 in that cell-free extracts exhibit a…