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Proto-Oncogene Proteins B-raf

Known as: Proto-Oncogene Proteins B-raf [Chemical/Ingredient], BRAF Kinases, Protein B-raf, Proto-Oncogene 
A raf kinase subclass found at high levels in neuronal tissue. The B-raf Kinases are MAP kinase kinase kinases that have specificity for MAP KINASE… 
National Institutes of Health

Related topics

Related topics

10 relations

Narrower (1)

BRAF protein, human
In BloodProcess of secretionantagonists & inhibitorsaspects of radiation effects

Broader (2)

Protein-Serine-Threonine KinasesProto-Oncogene Proteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Clinical Significance of BRAF and ZEB2 Expressions in Healthy Adjacent Tissue of Bladder Cancer
Background: Numerous molecular changes are involved in the development and progression of bladder cancer. Regular follow-up of… 
2018
2018
Insights into exchange factor directly activated by cAMP (EPAC) as potential target for cancer treatment
Cancer remains a global health problem and approximately 1.7 million new cancer cases are diagnosed every year worldwide… 
2014
2014
Abstract 2288: Pharmacological inhibition of B-Raf/MEK/ERK signaling suppresses DR5 expression and impairs cancer cell response to DR5 activation-induced apoptosis
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA Inhibition of B-Raf/MEK/ERK signaling is an effective… 
2013
2013
Expression analysis of B-Raf oncogene in V600E-negative benign and malignant tumors of the thyroid gland: correlation with late disease onset
B-Raf, a member of the Raf serine/threonine kinase family, is an intermediate molecule in the mitogen-activated protein kinase… 
2011
2011
ERK Crosstalks with 4 EBP 1 to Activate Cyclin D 1 Translation during Quinol-Thioether – Induced Tuberous Sclerosis Renal Cell Carcinoma
The mammalian target of rapamycin (mTOR) and mitogenactivated protein kinase signaling cascades have been implicated in a number… 
2008
2008
A phase II study of cetuximab (Cetuximab) with cisplatin and capecitabine (Xeloda) as 1st line treatment in advanced gastric cancer
15663 Background: The epidermal growth factor receptor (EGFR) commonly appears in 40–90% of gastric cancer, and preliminary data… 
Review
2005
Review
2005
5. MOLECULAR EPIDEMIOLOGY OF THYROID CANCER
Molecular biology studies have greatly enhanced our knowledge of thyroid tumorigenesis, although their impact in clinical… 
2004
2004
Advances in Brief B-Raf Is Dispensable for KRas-Mediated Oncogenesis in Human Cancer Cells 1
Oncogenic mutations in B-Raf and Kirsten-Ras (K-Ras) are mutually exclusive during human cancer pathogenesis. In an effort to… 
2000
2000
The Crk signaling pathway contributes to the bombesin-induced activation of the small GTPase Rap1 in Swiss 3T3 cells
Rap1 is a small GTPase implicated in cell proliferation and differentiation. The mechanisms how endogenous Rap1 is activated by… 
1996
1996
A specific association of ERK3 with B-Raf in rat hippocampus.
The possible formation of a stable complex between extracellular signal-regulated kinases (ERKs) and Raf protein kinases was… 
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