Proto-Oncogene Proteins B-raf

Known as: Proto-Oncogene Proteins B-raf [Chemical/Ingredient], BRAF Kinases, Protein B-raf, Proto-Oncogene 
A raf kinase subclass found at high levels in neuronal tissue. The B-raf Kinases are MAP kinase kinase kinases that have specificity for MAP KINASE… (More)
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
B-Raf is the most mutated gene in melanoma; however, the mechanism through which it promotes early melanomas remains uncertain… (More)
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Highly Cited
2007
Highly Cited
2007
IQGAP1 modulates several cellular functions, including cell-cell adhesion, transcription, cytoskeletal architecture, and selected… (More)
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Highly Cited
2006
Highly Cited
2006
The Ras-Raf-MEK-extracellular signal-regulated kinase (ERK) pathway participates in the control of many fundamental cellular… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND A recent phase III trial showed that the addition of bevacizumab, a monoclonal antibody to vascular endothelial growth… (More)
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Highly Cited
2004
Highly Cited
2004
cAMP can be either mitogenic or anti-mitogenic, depending on the cell type. We demonstrated previously that cAMP inhibited the… (More)
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Review
2003
Review
2003
A recent report has shown that activating mutations in the BRAF gene are present in a large percentage of human malignant… (More)
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Highly Cited
2000
Highly Cited
2000
B-Raf contains multiple Akt consensus sites located within its amino-terminal regulatory domain. One site, Ser(364), is conserved… (More)
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Highly Cited
1997
Highly Cited
1997
It has previously been shown that maximal activation of Raf-1 is produced by synergistic signals from oncogenic Ras and activated… (More)
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Highly Cited
1995
Highly Cited
1995
The c-Rmil/B-raf proto-oncogene is a member of the mil/raf family encoding serine/threonine protein kinases shown to be involved… (More)
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