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Proto-Oncogene Protein pp60 (c-src)

Known as: Protein src, Proto-Oncogene, pp60 c src, src Proto Oncogene Product 
Membrane-associated tyrosine-specific kinases encoded by the c-src genes. They have an important role in cellular growth control. Truncation of… 
National Institutes of Health

Related topics

Related topics

13 relations
In BloodProcess of secretionSRC geneantagonists & inhibitors

Narrower (4)

MATK protein, humanMatk protein, mouseProto-Oncogene Tyrosine-Protein Kinase Src, humanlyn protein-tyrosine kinase

Papers overview

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Highly Cited
2003
Highly Cited
2003
Nucleophosmin-anaplastic lymphoma kinase of anaplastic large-cell lymphoma recruits, activates, and uses pp60c-src to mediate its mitogenicity.
Anaplastic large-cell lymphomas (ALCLs) are lymphomas of T or null phenotype often associated with a chromosomal translocation, t… 
1996
1996
Tight‐binding inhibitory sequences against pp60 c−src identified using a random 15‐amino‐acid peptide library
1996
1996
Differential regulation of Src-family protein tyrosine kinases in GPI domains of T lymphocyte plasma membranes.
The association of glycosylphosphatidylinositol (GPI)-anchored cell surface glycoproteins with Src-family protein tyrosine… 
1995
1995
Amino-terminal regions of polyomavirus middle T antigen are required for interactions with protein phosphatase 2A
Polyomavirus middle T antigen (MT) is the major transforming protein of the virus. It functions through interactions with a… 
Highly Cited
1994
Highly Cited
1994
Identification of phosphorylated peptides from complex mixtures using negative-ion orifice-potential stepping and capillary liquid chromatography/electrospray ionization mass spectrometry.
A rapid method for identifying and characterizing sites of phosphorylation of peptides and proteins is described. High… 
1994
1994
Labeling of v‐Src and BCR‐ABL tyrosine kinases with [14C]herbimycin A and its use in the elucidation of the kinase inactivation mechanism
Highly Cited
1993
Highly Cited
1993
Translocation of pp60c-src from the plasma membrane to the cytosol after stimulation by platelet-derived growth factor.
1993
1993
Intestinal crypt cells contain higher levels of cytoskeletal-associated pp60c-src protein tyrosine kinase activity than do differentiated enterocytes.
Undifferentiated crypt cells from chicken small intestine contain 15-fold higher levels of tyrosine-phosphorylated proteins than… 
Highly Cited
1992
Highly Cited
1992
Polyoma virus middle T antigen-pp60c-src complex associates with purified phosphatidylinositol 3-kinase in vitro.
Highly Cited
1988
Highly Cited
1988
Elevated expression of pp60c-src alters a selective morphogenetic property of epithelial cells in vitro without a mitogenic effect
Madin-Darby canine kidney (MDCK) cells are highly differentiated and have retained the morphogenetic properties necessary to form… 
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