Proto-Oncogene Tyrosine-Protein Kinase Src, human

Known as: pp60c-src, p60src, SRC 
Proto-oncogene tyrosine-protein kinase Src (536 aa, ~60 kDa) is encoded by the human SRC gene. This protein is involved in both receptor-mediated… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1978-2018
020406019782018

Papers overview

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Highly Cited
2002
Highly Cited
2002
Vascular endothelial growth factor (VEGF) promotes vascular permeability (VP) and neovascularization, and is required for… (More)
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Highly Cited
2001
Highly Cited
2001
Loss of expression of neural cell-adhesion molecule (N-CAM) is implicated in the progression of tumour metastasis. Here we show… (More)
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Highly Cited
1999
Highly Cited
1999
Src kinase activity was found to protect endothelial cells from apoptosis during vascular endothelial growth factor (VEGF)-, but… (More)
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Highly Cited
1995
Highly Cited
1995
ANGIOGENESIS, the formation of new microvasculature by capillary sprouting, is crucial for tumour development1. Hypoxic regions… (More)
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Highly Cited
1995
Highly Cited
1995
Extracellular matrix controls capillary endothelial cell sensitivity to soluble mitogens by binding integrin receptors and… (More)
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Highly Cited
1994
Highly Cited
1994
Signaling by tyrosine kinase receptors is mediated by selective interactions between individual Src homology 2 (SH2) domains of… (More)
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Highly Cited
1993
Highly Cited
1993
Activation of the tyrosine kinase of the c-src gene product, pp60c-src, has been shown to occur in nearly every primary… (More)
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Highly Cited
1992
Highly Cited
1992
Targeted disruption of the c-src proto-oncogene in mice has shown that src expression is required for normal bone resorption… (More)
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Highly Cited
1992
Highly Cited
1992
THE high-affinity IgE receptor (FcɛRI), which is expressed on the surface of mast cells and basophils, has a central role in… (More)
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Highly Cited
1985
Highly Cited
1985
Polyoma middle-T antigen is required for viral transformation of cultured cells and for tumorigenesis in animals. Like many other… (More)
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