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Proto-Oncogene Tyrosine-Protein Kinase Src, human

Known as: pp60c-src, p60-SRC, p60src 
Proto-oncogene tyrosine-protein kinase Src (536 aa, ~60 kDa) is encoded by the human SRC gene. This protein is involved in both receptor-mediated… 
National Institutes of Health

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31 relations
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Broader (1)

Proto-Oncogene Protein pp60 (c-src)

Papers overview

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1993
1993
Intestinal crypt cells contain higher levels of cytoskeletal-associated pp60c-src protein tyrosine kinase activity than do differentiated enterocytes.
Undifferentiated crypt cells from chicken small intestine contain 15-fold higher levels of tyrosine-phosphorylated proteins than… 
Highly Cited
1991
Highly Cited
1991
Suppression of retroviral MA deletions by the amino-terminal membrane-binding domain of p60src
The molecular mechanism by which retroviral Gag proteins are directed to the plasma membrane for the formation of particles… 
Highly Cited
1989
Highly Cited
1989
Specific inhibitors of tyrosine-specific protein kinases: properties of 4-hydroxycinnamamide derivatives in vitro.
Inhibition by seven synthetic 4-hydroxycinnamamide derivatives, ST 271, ST 280, ST 458, ST 494, ST 633, ST 638, and ST 642, of… 
1989
1989
Alterations in the expression of pp60c-src and p56lck associated with butyrate-induced differentiation of human colon carcinoma cells.
The effects of butyrate-mediated differentiation of human colon carcinoma cells on the expression of src-related tyrosine protein… 
Highly Cited
1988
Highly Cited
1988
Activation of pp60c-src transforming potential by mutations altering the structure of an amino terminal domain containing residues 90-95.
The overexpression of the c-src gene product, pp60c-src, in avian and rodent embryo cells is not sufficient to induce cellular… 
Highly Cited
1987
Highly Cited
1987
Characterization of cDNA clones for the human c-yes gene
Three c-yes cDNA clones were obtained from poly(A)+ RNA of human embryo fibroblasts. Sequence analysis of the clones showed that… 
Highly Cited
1987
Highly Cited
1987
Expression of c-src in cultured human neuroblastoma and small-cell lung carcinoma cell lines correlates with neurocrine differentiation
Human cell lines with neuronal and neuroendocrine features were examined for their expression of pp60c-src, the cellular homolog… 
Highly Cited
1985
Highly Cited
1985
N-terminal deletions in Rous sarcoma virus p60src: effects on tyrosine kinase and biological activities and on recombination in tissue culture with the cellular src gene
We have constructed deletions within the region of cloned Rous sarcoma virus DNA coding for the N-terminal 30 kilodaltons of… 
Highly Cited
1978
Highly Cited
1978
Comparison of the expression of the src gene of Rous sarcoma virus in vitro and in vivo
We have compared the polypeptide products of the src gene of several strains of Rous sarcoma virus produced by in vitro… 
Highly Cited
1978
Highly Cited
1978
In vitro synthesis of a functional avian sarcoma virus transforming-gene product
A SINGLE avian sarcoma virus (ASV) gene (src) is responsible for the induction and maintenance of cell transformation in vitro… 
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