Proto-Oncogene Protein c-kit

Known as: Proto-Oncogene Proteins c-kit [Chemical/Ingredient], c-kit, p145, c kit Receptor 
A protein-tyrosine kinase receptor that is specific for STEM CELL FACTOR. This interaction is crucial for the development of hematopoietic, gonadal… (More)
National Institutes of Health

Papers overview

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Highly Cited
2000
Highly Cited
2000
STI 571 (formerly known as CGP 57148B) is a known inhibitor of the c-abl, bcr-abl, and platelet-derived growth-factor receptor… (More)
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Highly Cited
1999
Highly Cited
1999
Spontaneous mast cell tumors (MCT) are the most common malignant neoplasm in the dog, representing between 7% and 21% of all… (More)
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Highly Cited
1995
Highly Cited
1995
Both stem cells and mast cells express c-kit and proliferate after exposure to c-kit ligand. Mutations in c-kit may enhance or… (More)
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Highly Cited
1991
Highly Cited
1991
The c-kit proto-oncogene encodes a receptor tyrosine kinase that is thought to play an important role in hematopoiesis. In a… (More)
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Highly Cited
1990
Highly Cited
1990
We report the purification and N-terminal amino acid sequence of a novel mast cell growth factor, termed MGF, from the… (More)
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Highly Cited
1990
Highly Cited
1990
Mutations at the steel locus (Sl) of the mouse affect the same cellular targets as mutations at the white spotting locus (W… (More)
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Highly Cited
1990
Highly Cited
1990
We have cloned a partial cDNA encoding murine stem cell factor (SCF) and show that the gene is syntenic with the Sl locus on… (More)
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Highly Cited
1990
Highly Cited
1990
Recently, it has been shown that the c-kit proto-oncogene is encoded at the white spotting (W) locus in mice. Mutations of this… (More)
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Highly Cited
1989
Highly Cited
1989
The proto-oncogene c-kit, a transmembrane tyrosine protein kinase receptor for an unknown ligand, was shown recently to map to… (More)
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Highly Cited
1987
Highly Cited
1987
Structural features of v-kit, the oncogene of HZ4 feline sarcoma virus, suggested that this gene arose by transduction and… (More)
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