Protein Unfolding

Known as: Unfolding, Protein 
The process of assisting in the disassembly of non-covalent linkages in a protein or protein aggregate, often where the proteins are in a non… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1965-2018
02040608019652018

Papers overview

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Highly Cited
2011
Highly Cited
2011
AAA(+) unfoldases denature and translocate polypeptides into associated peptidases. We report direct observations of mechanical… (More)
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Highly Cited
2009
Highly Cited
2009
Blood clots and thrombi consist primarily of a mesh of branched fibers made of the protein fibrin. We propose a molecular basis… (More)
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Highly Cited
2009
Highly Cited
2009
We use single silicon nitride nanopores to study folded, partially folded, and unfolded single proteins by measuring their… (More)
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Highly Cited
2008
Highly Cited
2008
Hypochlorous acid (HOCl), the active ingredient in household bleach, is an effective antimicrobial produced by the mammalian host… (More)
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Highly Cited
2006
Highly Cited
2006
Circular dichroism (CD) is an excellent spectroscopic technique for following the unfolding and folding of proteins as a function… (More)
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Highly Cited
2002
Highly Cited
2002
We relate the unfolding of a protein to its loss of structural stability or rigidity. Rigidity and flexibility are well defined… (More)
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Highly Cited
2001
Highly Cited
2001
Amyloid fibril formation and deposition is a common feature of a wide range of fatal diseases including spongiform… (More)
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Highly Cited
1999
Highly Cited
1999
The nature of the interaction responsible for the inhibition of protein unfolding and subsequent damage by sugars during… (More)
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Highly Cited
1996
Highly Cited
1996
Peptidylarginine deiminases, which are commonly found in mammalian cells, catalyze the deimination of protein-bound arginine… (More)
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Highly Cited
1995
Highly Cited
1995
Denaturant m values, the dependence of the free energy of unfolding on denaturant concentration, have been collected for a large… (More)
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