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Protein Quaking

Known as: Homolog Of Mouse Quaking QKI (KH Domain RNA Binding Protein), Quaking Homolog, KH Domain RNA Binding, RNA Binding Protein HQK 
Protein quaking (341 aa, ~38 kDa) is encoded by the human QKI gene. This protein is involved in mRNA biosynthesis, mRNA splicing, mRNA stabilization… Expand
National Institutes of Health

Related topics

Related topics

6 relations
KH DomainLigand BindingQKI geneRNA Binding
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
RNA-binding Protein Quaking Stabilizes Sirt2 mRNA during Oligodendroglial Differentiation*
Myelination is controlled by timely expression of genes involved in the differentiation of oligodendrocyte precursor cells (OPCs… Expand
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2016
2016
The RNA-binding protein quaking maintains endothelial barrier function and affects VE-cadherin and β-catenin protein expression
Proper regulation of endothelial cell-cell contacts is essential for physiological functioning of the endothelium… Expand
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Highly Cited
2015
Highly Cited
2015
The RNA Binding Protein Quaking Regulates Formation of circRNAs
Circular RNAs (circRNAs), formed by non-sequential back-splicing of pre-mRNA transcripts, are a widespread form of non-coding RNA… Expand
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2014
2014
A cytoplasmic quaking I isoform regulates the hnRNP F/H-dependent alternative splicing pathway in myelinating glia
The selective RNA-binding protein quaking I (QKI) plays important roles in controlling alternative splicing (AS). Three QKI… Expand
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2014
2014
Evolutionary Dynamics of GLD-1–mRNA Complexes in Caenorhabditis Nematodes
Given the large number of RNA-binding proteins and regulatory RNAs within genomes, posttranscriptional regulation may be an… Expand
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2014
2014
The tumor suppressing effects of QKI-5 in prostate cancer: a novel diagnostic and prognostic protein.
In recent years, the RNA-binding protein quaking 5 (QKI-5) has been recognized as a novel tumor suppressor in many cancers. To… Expand
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2011
2011
HSV-1 Cgal+ infection promotes quaking RNA binding protein production and induces nuclear-cytoplasmic shuttling of quaking I-5 isoform in human hepatoma cells.
Herpesvirus type 1 (HSV-1) based oncolytic vectors arise as a promising therapeutic alternative for neoplastic diseases including… Expand
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2010
2010
Quaking I controls a unique cytoplasmic pathway that regulates alternative splicing of myelin-associated glycoprotein.
Precise control of alternative splicing governs oligodendrocyte (OL) differentiation and myelination in the central nervous… Expand
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Highly Cited
2010
Highly Cited
2010
RNA-binding protein quaking, a critical regulator of colon epithelial differentiation and a suppressor of colon cancer.
BACKGROUND & AIMS Colon cancer is one of the best understood neoplasms from a genetic perspective, yet it remains the second most… Expand
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2007
2007
The selective RNA-binding protein quaking I (QKI) is necessary and sufficient for promoting oligodendroglia differentiation.
Quaking I (QKI) is a selective RNA-binding protein essential for myelination of the central nervous system. Three QKI isoforms… Expand
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