Solution Structure of the QUA1 Dimerization Domain of pXqua, the Xenopus Ortholog of Quaking

Abstract

The STAR protein family member Quaking is essential for early development in vertebrates. For example, in oligodendrocyte cells it regulates the splicing, localization, translation and lifetime of a set of mRNAs that code for crucial components of myelin. The Quaking protein contains three contiguous conserved regions: a QUA1 oligomerization element… (More)
DOI: 10.1371/journal.pone.0057345

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