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Protein Atonal Homolog 1, human

Known as: bHLHa14, Protein Atonal Homolog 1, Class A Basic Helix-Loop-Helix Protein 14 
Protein atonal homolog 1 (354 aa, ~38 kDa) is encoded by the human ATOH1 gene. This protein is involved in the activation of E-box dependent gene… 
National Institutes of Health

Related topics

Related topics

9 relations
ATOH1 geneDNA-Binding ProteinsGenes, RegulatorNeurogenesis

Papers overview

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2016
2016
DAPT mediates atoh1 expression to induce hair cell-like cells.
Hearing loss is currently an incurable degenerative disease characterized by a paucity of hair cells (HCs), which cannot be… 
2012
2012
Hath1 inhibits proliferation of colon cancer cells probably through up-regulating expression of Muc2 and p27 and down-regulating expression of cyclin D1.
Previous studies showed that Math1 homologous to human Hath1 can cause mouse goblet cells to differentiate. In this context it is… 
2011
2011
Longitudinal cell formation in the entire human small intestine is correlated with the localization of Hath1 and Klf4
BackgroundDouble balloon endoscopy (DBE) enables the observation and collection of viable specimens from the entire intestine… 
2010
2010
S1766 Regulation of Goblet Cell Differentiation Factors HATH1 and KLF4 in Intestinal Epithelial Cells
2010
2010
Expression of Reg IV and Hath1 in neuroendocrine neoplasms.
Reg IV (RELP), a Regenerating protein family member, is constitutively expressed in neuroendocrine cells of the intestinal mucosa… 
2008
2008
[Overexpression of Hath1 induces production of hair cell-like cells in greater epithelial ridge cell cultures from postnatal rat cochlea].
OBJECTIVE To investigate the effect of Hath1 (human atonal homolog 1) overexpression on greater epithelial ridge (GER) cells from… 
2008
2008
Proteasomal degradation of Atoh1 by aberrant Wnt signaling maintains the undifferentiated state of colon cancer.
2004
2004
Proliferation and Tumorigenesis of Colon Cancer Cells Hath 1 , Down-Regulated in Colon Adenocarcinomas , Inhibits
A striking feature of colon tumors is the significant reduction of goblet cells. Although targeted deletion of Math1 in mice… 
2003
2003
Expression of Developmentally Regulated Transcription Factors in Merkel Cell Carcinoma
We have examined a number of developmentally regulated transcription factors for expression in Merkel cells and MCC cell lines… 
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