Hui-min Du

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Human telomerase reverse transcriptase (hTERT) has been identified as an ideal tumor-associated antigen (TAA). Use of a synthetic hTERT epitope peptide to pulse dendritic cells can induce autologous T cell anti-tumor immune responses, but such responses induced by a single epitope peptide have been shown to be weak and a narrow-spectrum. Here, we designed(More)
BACKGROUND The purpose was to estimate the incidence and characteristics of childhood inflammatory bowel disease (IBD) during 2000-2010 in Shanghai, China. METHODS IBD patients between the ages of 0 and 18 years old were identified by survey of computerized medical information. Relevant data were extracted from their corresponding medical records. (More)
Previous studies showed that Math1 homologous to human Hath1 can cause mouse goblet cells to differentiate. In this context it is important that the majority of colon cancers have few goblet cells. In the present study, the potential role of Hath1 in colon carcinogenesis was investigated. Sections of paraffin-embedded tissues were used to investigate the(More)
AIM To study the antigen specific anti-tumor effect of cytotoxic T lymphocytes(CTLs), which was induced by human telomerase reverse transcriptase (hTERT)-related multiple epitope peptides impulsed myeloid dendritic cells(mDCs), against human leukocyte antigen (HLA)-A24(+) tumor cells. METHODS Four branches of multiple antigen peptides (MAPs) of hTERT(More)
Cognitive impairment has been a common complication of diabetic. Recent evidences have pointed out angiotensin-IV (Ang-IV) can facilitate memory acquisition and recovery, whether it also can improve cognitive functions of diabetic rats with cognition disorder and the possible mechanisms if it really can are yet unknown. In this study, 45 Sprague Dawley (SD)(More)
Cognitive impairment is a common complication of diabetes. Hippocampus plays an important role in cognitive function. In hyperglycemia, synaptophysin, a crucial synaptic vesicle membrane protein in hippocampus neuron is found to be down-regulated. Recent evidences have shown that angiotensin IV can facilitate memory acquisition and recovery. However,(More)
IP address lookup is a key issue in modern high performance router design. In order to improve the efficiency and scalability of IP address lookup, a novel Scalable Parallel IP Address Lookup Architecture (SPALA) based on 2D-Torus interconnection network is proposed. As an application of Massively Parallel Processing (MPP) technology, IP address lookup, a(More)
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