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Prostate cancer, familial

Known as: Hereditary prostate cancer, PRCA1, HPC1 
National Institutes of Health

Related topics

Related topics

2 relations
HPC1 gene

Broader (1)

Prostatic Neoplasms

Papers overview

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2011
2011
Genome‐wide linkage scan for prostate cancer susceptibility in Finland: Evidence for a novel locus on 2q37.3 and confirmation of signal on 17q21‐q22
Genome‐wide linkage studies have been used to localize rare and highly penetrant prostate cancer (PRCA) susceptibility genes… 
2007
2007
Germline Mutations in the BRCA2 Gene and Susceptibility to Hereditary Prostate Cancer
Purpose: Several epidemiologic studies have reported that carriers of germline mutations in the BRCA2 gene have an increased risk… 
Review
2006
Review
2006
Genetic Susceptibility to Aggressive Prostate Cancer
In 2006, ∼234,460 men in the U.S. will be diagnosed with prostate cancer, and >27,000 deaths will be attributed to the disease… 
Highly Cited
2003
Highly Cited
2003
Linkage analysis of prostate cancer susceptibility: confirmation of linkage at 8p22–23
Frequent loss of heterogeneity in prostate cancer cells and linkage studies of families affected by hereditary prostate cancer… 
2003
2003
Evaluation of SRD5A2 sequence variants in susceptibility to hereditary and sporadic prostate cancer
The 5 alpha‐reductase type II (SRD5A2) catalyzes the conversion of testosterone into the more potent androgen… 
2003
2003
Evaluation of DLC1 as a prostate cancer susceptibility gene: mutation screen and association study.
Highly Cited
2001
Highly Cited
2001
Cloning and characterization of 13 novel transcripts and the human RGS8 gene from the 1q25 region encompassing the hereditary prostate cancer (HPC1) locus.
The aim of this study was to develop a saturated transcript map of the region encompassing the HPC1 locus to identify the… 
2000
2000
Replication linkage study for prostate cancer susceptibility genes
Since the publication of the first genome screen for prostate cancer (CaP) 5 years ago, over a dozen linkage studies have… 
1998
1998
Allelic imbalance in familial and sporadic prostate cancer at the putative human prostate cancer susceptibility locus, HPC1. CRC/BPG UK Familial Prostate Cancer Study Collaborators. Cancer Research…
A recent report has provided strong evidence for a major prostate cancer susceptibility locus (HPC1) on chromosome 1q24-25 (Smith… 
Highly Cited
1997
Highly Cited
1997
Interference with the expression of a novel human polycomb protein, hPc2, results in cellular transformation and apoptosis
Polycomb (Pc) is involved in the stable and heritable repression of homeotic gene activity during Drosophila development. Here… 
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