Prostate cancer, familial

Known as: Hereditary prostate cancer, PRCA1, HPC1 
 
National Institutes of Health

Related topics

Related topics

2 relations
HPC1 gene

Broader (1)

Prostatic Neoplasms

Papers overview

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Highly Cited
2012
Highly Cited
2012
Germline mutations in HOXB13 and prostate-cancer risk.
BACKGROUND Family history is a significant risk factor for prostate cancer, although the molecular basis for this association is… (More)
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Highly Cited
2007
Highly Cited
2007
Polycomb-group oncogenes EZH2, BMI1, and RING1 are overexpressed in prostate cancer with adverse pathologic and clinical features.
OBJECTIVES Polycomb group (PcG) proteins are involved in maintenance of cell identity and proliferation. The protein EZH2 is… (More)
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2004
2004
Combined genome-wide scan for prostate cancer susceptibility genes.
BACKGROUND Prostate cancer represents a substantial public health burden worldwide. It is the second leading cause of cancer… (More)
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Highly Cited
2003
Highly Cited
2003
Effects of RNase L mutations associated with prostate cancer on apoptosis induced by 2',5'-oligoadenylates.
The RNASEL gene, a strong candidate for the hereditary prostate cancer 1 allele (HPC1), encodes a single-stranded specific… (More)
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Highly Cited
2003
Highly Cited
2003
CHEK2 variants associate with hereditary prostate cancer
Recently, variants in CHEK2 gene were shown to associate with sporadic prostate cancer in the USA. In the present study from… (More)
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2003
2003
Genome linkage screen for prostate cancer susceptibility loci: results from the Mayo Clinic Familial Prostate Cancer Study.
Prostate cancer is one of the most common cancers among men and has long been recognized to occur in familial clusters. Brothers… (More)
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Highly Cited
2002
Highly Cited
2002
Germline mutations and sequence variants of the macrophage scavenger receptor 1 gene are associated with prostate cancer risk
Deletions on human chromosome 8p22–23 in prostate cancer cells and linkage studies in families affected with hereditary prostate… (More)
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2001
2001
Evaluation of linkage and association of HPC2/ELAC2 in patients with familial or sporadic prostate cancer.
To investigate the relationship between HPC2/ELAC2 and prostate cancer risk, we performed the following analyses: (1) a linkage… (More)
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Highly Cited
2000
Highly Cited
2000
Evidence for a prostate cancer-susceptibility locus on chromosome 20.
Recent studies suggest that hereditary prostate cancer is a complex disease involving multiple susceptibility genes and variable… (More)
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1999
1999
Familial and hereditary prostate cancer in southern Sweden. A population-based case-control study.
The objectives of this study were to investigate the effect of family history on prostate cancer risk, to estimate the incidence… (More)
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