Prostate cancer, familial

BACKGROUND Family history is a significant risk factor for prostate cancer, although the molecular basis for this association is… Expand

OBJECTIVES Polycomb group (PcG) proteins are involved in maintenance of cell identity and proliferation. The protein EZH2 is… Expand

The RNASEL gene, a strong candidate for the hereditary prostate cancer 1 allele (HPC1), encodes a single-stranded specific… Expand

Deletions on human chromosome 8p22–23 in prostate cancer cells and linkage studies in families affected with hereditary prostate… Expand

To investigate the relationship between HPC2/ELAC2 and prostate cancer risk, we performed the following analyses: (1) a linkage… Expand

Recent studies suggest that hereditary prostate cancer is a complex disease involving multiple susceptibility genes and variable… Expand

It is with enormous excitement, last month, that the prostate cancer–mapping community acknowledges the cloning and… Expand

The African American Hereditary Prostate Cancer (AAHPC) Study is an ongoing multicenter genetic linkage study organized by Howard… Expand

Over 200,000 new prostate cancer cases are diagnosed in the United States each year, accounting for more than 35% of all cancer… Expand

A monoclonal antibody (mAb), HPC-1, labels the plasma membrane of the amacrine cell soma and inner plexiform layer in rat retina… Expand