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Prostate cancer, familial

Known as: Hereditary prostate cancer, PRCA1, HPC1 
National Institutes of Health

Related topics

Related topics

2 relations
HPC1 gene

Broader (1)

Prostatic Neoplasms

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
A major locus for hereditary prostate cancer in Finland: localization by linkage disequilibrium of a haplotype in the HPCX region
Background: Prostate cancer (PRCA) is the most common cancer in males in the western world. In Finland PRCA has an age-adjusted… 
2005
2005
Population‐based risk assessment for other cancers in relatives of hereditary prostate cancer (HPC) cases
To identify associations of other cancers with hereditary prostate cancer (HPC) we estimated relative risks (RRs) of 36 different… 
Highly Cited
2004
Highly Cited
2004
−160C/A polymorphism in the E‐cadherin gene promoter and risk of hereditary, familial and sporadic prostate cancer
The E‐cadherin (CDH1) gene has been associated with prostate carcinogenesis. The C/A polymorphism −160 base pairs relative to the… 
Highly Cited
2003
Highly Cited
2003
Linkage analysis of prostate cancer susceptibility: confirmation of linkage at 8p22–23
Frequent loss of heterogeneity in prostate cancer cells and linkage studies of families affected by hereditary prostate cancer… 
2001
2001
Evidence for a prostate cancer linkage to chromosome 20 in 159 hereditary prostate cancer families
Abstract. Prostate cancer is the most common malignancy diagnosed in men in the US. Genetic susceptibility to prostate cancer has… 
Highly Cited
2001
Highly Cited
2001
Cloning and characterization of 13 novel transcripts and the human RGS8 gene from the 1q25 region encompassing the hereditary prostate cancer (HPC1) locus.
The aim of this study was to develop a saturated transcript map of the region encompassing the HPC1 locus to identify the… 
2000
2000
Replication linkage study for prostate cancer susceptibility genes
Since the publication of the first genome screen for prostate cancer (CaP) 5 years ago, over a dozen linkage studies have… 
Highly Cited
1998
Highly Cited
1998
Biological aggressiveness of hereditary prostate cancer: long-term evaluation following radical prostatectomy.
Highly Cited
1998
Highly Cited
1998
Characteristics of prostate cancer in families potentially linked to the hereditary prostate cancer 1 (HPC1) locus.
Highly Cited
1997
Highly Cited
1997
Interference with the expression of a novel human polycomb protein, hPc2, results in cellular transformation and apoptosis
Polycomb (Pc) is involved in the stable and heritable repression of homeotic gene activity during Drosophila development. Here… 
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