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Prostate cancer, familial

Known as: Hereditary prostate cancer, PRCA1, HPC1 
National Institutes of Health

Related topics

Related topics

2 relations
HPC1 gene

Broader (1)

Prostatic Neoplasms

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Germline mutations in HOXB13 and prostate-cancer risk.
BACKGROUND Family history is a significant risk factor for prostate cancer, although the molecular basis for this association is… Expand
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Highly Cited
2007
Highly Cited
2007
Polycomb-group oncogenes EZH2, BMI1, and RING1 are overexpressed in prostate cancer with adverse pathologic and clinical features.
OBJECTIVES Polycomb group (PcG) proteins are involved in maintenance of cell identity and proliferation. The protein EZH2 is… Expand
Highly Cited
2003
Highly Cited
2003
Effects of RNase L mutations associated with prostate cancer on apoptosis induced by 2',5'-oligoadenylates.
The RNASEL gene, a strong candidate for the hereditary prostate cancer 1 allele (HPC1), encodes a single-stranded specific… Expand
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Highly Cited
2002
Highly Cited
2002
Germline mutations and sequence variants of the macrophage scavenger receptor 1 gene are associated with prostate cancer risk
Deletions on human chromosome 8p22–23 in prostate cancer cells and linkage studies in families affected with hereditary prostate… Expand
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Highly Cited
2001
Highly Cited
2001
Linkage and association studies of prostate cancer susceptibility: evidence for linkage at 8p22-23.
Multiple lines of evidence have implicated the short arm of chromosome 8 as harboring genes important in prostate carcinogenesis… Expand
Highly Cited
2000
Highly Cited
2000
Evidence for a prostate cancer-susceptibility locus on chromosome 20.
Recent studies suggest that hereditary prostate cancer is a complex disease involving multiple susceptibility genes and variable… Expand
Review
2000
Review
2000
Genetics of prostate cancer: too many loci, too few genes.
It is with enormous excitement, last month, that the prostate cancer–mapping community acknowledges the cloning and… Expand
Highly Cited
2000
Highly Cited
2000
Recruitment experience in the first phase of the African American Hereditary Prostate Cancer (AAHPC) study.
The African American Hereditary Prostate Cancer (AAHPC) Study is an ongoing multicenter genetic linkage study organized by Howard… Expand
Highly Cited
1998
Highly Cited
1998
Evidence for a prostate cancer susceptibility locus on the X chromosome.
Over 200,000 new prostate cancer cases are diagnosed in the United States each year, accounting for more than 35% of all cancer… Expand
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Highly Cited
1992
Highly Cited
1992
Cloning and sequence analysis of cDNA for a neuronal cell membrane antigen, HPC-1.
A monoclonal antibody (mAb), HPC-1, labels the plasma membrane of the amacrine cell soma and inner plexiform layer in rat retina… Expand
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