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HPC1 gene

Known as: HPC1, hereditary prostate cancer 1 
National Institutes of Health

Related topics

Related topics

3 relations
ELAC2 protein, humanPROSTATE CANCER, HEREDITARY, X-LINKED 1Prostate cancer, familial

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
New insights into the role of RNase L in innate immunity.
The interferon (IFN)-inducible 2'-5'-oligoadenylate synthetase (OAS)/RNase L pathway blocks infections by some types of viruses… 
Highly Cited
2007
Highly Cited
2007
Polycomb-group oncogenes EZH2, BMI1, and RING1 are overexpressed in prostate cancer with adverse pathologic and clinical features.
Highly Cited
2004
Highly Cited
2004
Unique polycomb gene expression pattern in Hodgkin's lymphoma and Hodgkin's lymphoma-derived cell lines.
Highly Cited
2003
Highly Cited
2003
Poorly differentiated breast carcinoma is associated with increased expression of the human polycomb group EZH2 gene.
Highly Cited
2003
Highly Cited
2003
Production, purification, and functional analysis of recombinant human and mouse 17beta-hydroxysteroid dehydrogenase type 7.
Highly Cited
2002
Highly Cited
2002
Germline mutations in the ribonuclease L gene in families showing linkage with HPC1
Although prostate cancer is the most common non-cutaneous malignancy diagnosed in men in the United States, little is known about… 
Highly Cited
2002
Highly Cited
2002
Germline alterations of the RNASEL gene, a candidate HPC1 gene at 1q25, in patients and families with prostate cancer.
The RNASEL gene (2',5'-oligoisoadenylate-synthetase dependent) encodes a ribonuclease that mediates the antiviral and apoptotic… 
Highly Cited
1998
Highly Cited
1998
Evidence for a prostate cancer susceptibility locus on the X chromosome.
Over 200,000 new prostate cancer cases are diagnosed in the United States each year, accounting for more than 35% of all cancer… 
Highly Cited
1997
Highly Cited
1997
Prostate cancer susceptibility locus on chromosome 1q: a confirmatory study.
Highly Cited
1992
Highly Cited
1992
Cloning and sequence analysis of cDNA for a neuronal cell membrane antigen, HPC-1.
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