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Promethazine

Known as: 10-[2-(dimethylamino)Propyl]phenothiazine, N-(2'-dimethylamino-2'-Methyl)ethylphenothiazine, 10H-Phenothiazine-10-ethanamine, N,N,alpha-trimethyl- 
A phenothiazine derivative with antiemetic and antihistaminic properties. Promethazine antagonizes the central and peripheral effects of histamine… 
National Institutes of Health

Related topics

Related topics

41 relations

Narrower (17)

1 ML Promethazine Hydrochloride 25 MG/ML InjectionAtosilCodeine / PromethazineDiphergan

Broader (6)

Anti-Allergic AgentsAntihistaminesHistamine H1 AntagonistsPropylamines
Histamine H1 Receptor Antagonists [MoA]In BloodIsopromethazineMotion Sickness

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
MEDICAMENTOS ANTIDEPRESSIVOS E ANTIPSICÓTICOS PRESCRITOS NO CENTRO DE ATENÇÃO PSICOSSOCIAL (CAPS) DO MUNICÍPIO DE PORCIÚNCULA – RJ
Foi realizada uma pesquisa no Centro de Atencao Psicossocial (CAPS) localizado no municipio de Porciuncula, Estado do Rio de… 
2009
2009
H 1 ANTIHISTAMINES IN ALLERGIC DISEASE
Histamine (one of the key mediators released from mast cells and basophils), plays a major role in the pathophysiology of… 
1986
1986
Automated flow injection spectrophotometric determination of some phenothiazines using iron perchlorate: applications in drug assays, content uniformity and dissolution studies.
An automated flow injection determination of some phenothiazine derivatives, based on their oxidation with iron(III) in a… 
1982
1982
High-pressure liquid chromatographic determination of promethazine plasma levels in the dog after oral, intramuscular, and intravenous dosage.
Plasma levels of promethazine were determined using a high-pressure liquid chromatographic procedure incorporating a fixed… 
1977
1977
H1- and H2-receptor mediated responses to histamine on contractility and cyclic AMP of atrial and papillary muscles from guinea-pig hearts
AbstractOn guinea-pig heart we investigated whether cyclic AMP serves as a messenger for H1- and/or H2-mediated responses to… 
1977
1977
Morphine and Promethazine as Intravenous Premedicants
Los Angeles, Californiatt Two hundred seventy patients received morphine 5 mg or 10 mg alone or with promethazine 6.25 mg, 12.5… 
1974
1974
Blockade of cardiac histamine receptors by promethazine.
The inotropic and chronotropic effects of histamine on the isolated perfused guinea pig heart were antagonized by promethazine… 
1973
1973
Effects of Meperidine and Promethazine During Labor
Thirty-two patients were evaluated to determine the effects of meperidine and promethazine administered during active labor, with… 
1965
1965
Action of 5-hydroxytryptamine on the human stomach, duodenum, and jejunum in vitro.
These pharmacological studies on human alimentary smooth muscle show that different regions of gut respond differently. Where a… 
1965
1965
The effects of an antihistamine (promethazine) on the reaction of tendons to trauma (a histological study).
As a part of a continuing study on the healing of flexor tendons, the effects of an antihistamine–antiserotonin compound…