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Proinsulin, human

Known as: Insulin Precursor, Proinsulin 
Proinsulin (110 aa, ~12 kDa) is encoded by the human INS gene. This protein plays a role in the modulation of glucose metabolism.
National Institutes of Health

Papers overview

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Highly Cited
1999
Highly Cited
1999
Postmenopausal overweight women have an increased risk of breast cancer. The link between obesity and breast cancer could be… 
Review
1994
Review
1994
SummaryThe insulin storage granule of the pancreatic beta cell is assembled within the trans Golgi network from around 50 or so… 
Highly Cited
1988
Highly Cited
1988
IgG proinsulin autoantibodies (IgG-PAAs) have been found in a fraction of sera from patients with newly diagnosed insulin… 
Highly Cited
1978
Highly Cited
1978
Pancreatic islets contain an enzyme system which catalyzes the donation of hydrogen from NAD(P)H to menadione (2-methyl-1,4… 
Highly Cited
1977
Highly Cited
1977
We have measured the specific binding of 125I-insulin to insulin receptors on circulating monocytes from 5 patients with… 
Highly Cited
1974
Highly Cited
1974
Radioimmunoassay of human C-peptide was established using antiserum to synthetic human connecting peptide and synthetic… 
Highly Cited
1972
Highly Cited
1972
ABSTRACT The effect of the chronic administration of glyburide, a potent sulfonylurea, on plasma glucose, insulin and proinsulin…