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Programmed Death Ligand 2 Protein

Known as: Programmed Cell Death 1 Ligand 2, PDCD1L2, PDCD1 Ligand 2 
Programmed cell death 1 ligand 2 (273 aa, ~31 kDa) is encoded by the human PDCD1LG2 gene. This protein is involved in the modulation of both T-cell… 
National Institutes of Health

Related topics

Related topics

5 relations
B7-DC antigenImmune System ProcessesPDCD1LG2 genePDCD1LG2 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Expression of Programmed Cell Death 1 Ligand 2 (PD-L2) Is a Distinguishing Feature of Primary Mediastinal (Thymic) Large B-cell Lymphoma and Associated With PDCD1LG2 Copy Gain
Primary mediastinal (thymic) large B-cell lymphoma (PMBL) and diffuse large B-cell lymphoma (DLBCL) are tumors with distinct… 
Highly Cited
2012
Highly Cited
2012
Enhancement of tumor immunotherapy by deletion of the A2A adenosine receptor
The A2A adenosine receptor plays a critical and non-redundant role in suppressing inflammation at sites of hypoxia and tissue… 
Highly Cited
2010
Highly Cited
2010
Alternatively activated macrophages inhibit T-cell proliferation by Stat6-dependent expression of PD-L2.
Alternatively activated macrophages (AAM) accumulate in tissues during Th2-associated immune responses like helminth infections… 
Highly Cited
2010
Highly Cited
2010
siRNA silencing of PD-L1 and PD-L2 on dendritic cells augments expansion and function of minor histocompatibility antigen-specific CD8+ T cells.
Tumor relapse after human leukocyte antigen-matched allogeneic stem cell transplantation (SCT) remains a serious problem, despite… 
Highly Cited
2008
Highly Cited
2008
Crystal structure of the complex between programmed death-1 (PD-1) and its ligand PD-L2
Programmed death-1 (PD-1) is a member of the CD28/B7 superfamily that delivers negative signals upon interaction with its two… 
Highly Cited
2008
Highly Cited
2008
Reprogrammed FoxP3+ T Regulatory Cells Become IL-17+ Antigen-Specific Autoimmune Effectors In Vitro and In Vivo1
Lymphocyte differentiation from naive CD4+ T cells into mature Th1, Th2, Th17, or T regulatory cell (Treg) phenotypes has been… 
Highly Cited
2007
Highly Cited
2007
The Function of Donor versus Recipient Programmed Death-Ligand 1 in Corneal Allograft Survival1
Programmed death-ligand (PD-L)1 and PD-L2, newer B7 superfamily members, are implicated in the negative regulation of immune… 
Highly Cited
2006
Highly Cited
2006
Predominant expression of B7-H1 and its immunoregulatory roles in oral squamous cell carcinoma.
Highly Cited
2004
Highly Cited
2004
Synthesis, structure, theoretical studies, and Ligand exchange reactions of monomeric, T-shaped arylpalladium(II) halide complexes with an additional, weak agostic interaction.
A series of monomeric arylpalladium(II) complexes LPd(Ph)X (L = 1-AdPtBu2, PtBu3, or Ph5FcPtBu2 (Q-phos); X = Br, I, OTf… 
Highly Cited
2003
Highly Cited
2003
Blockade of B7-H1 Suppresses the Development of Chronic Intestinal Inflammation 1
A newly identified costimulatory molecule, programmed death-1 (PD-1), provides a negative signal that is essential for immune… 
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