Progesterone Antagonist

Known as: Anti-Progestin, Anti-progesterones, antiprogestin 
A substance that prevents cells from making or using progesterone (a hormone that plays a role in the menstrual cycle and pregnancy). Antiprogestins… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Uterine leiomyomata (ULs) represent the most common tumor in women and can cause abnormal uterine bleeding, large pelvic masses… (More)
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Highly Cited
2006
Highly Cited
2006
Women with mutations in the breast cancer susceptibility gene BRCA1 are predisposed to breast and ovarian cancers. Why the BRCA1… (More)
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Highly Cited
2006
Highly Cited
2006
During early pregnancy in ruminants, progesterone (P4) from the corpus luteum and interferon tau (IFNT) from the conceptus act on… (More)
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Review
2005
Review
2005
Since the discovery of the antiprogestin mifepristone, hundreds of similar compounds have been synthesized, which can be grouped… (More)
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Highly Cited
2003
Highly Cited
2003
Charcot-Marie-Tooth disease (CMT) is the most common inherited neuropathy. The predominant subtype, CMT-1A, accounts for more… (More)
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Highly Cited
1998
Highly Cited
1998
The physiological effects of progestins are mediated by the progesterone receptor, a member of the steroid/nuclear receptor… (More)
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Highly Cited
1998
Highly Cited
1998
A hexahistidine-tagged C-terminal nucleotide-binding domain (H6-NBD2) from mouse P-glycoprotein was designed, overexpressed, and… (More)
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Highly Cited
1997
Highly Cited
1997
Steroid receptor antagonists, such as the antiestrogen tamoxifen or the antiprogestin RU486, can have inappropriate agonist-like… (More)
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Highly Cited
1994
Highly Cited
1994
Human progesterone target tissues contain two progesterone receptors: B-receptors (hPRB), which are 933 amino acids in length… (More)
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Highly Cited
1994
Highly Cited
1994
Because progesterone antagonists are growth inhibitors, they are in Phase III clinical trials for the treatment of breast cancer… (More)
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