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Progesterone Antagonist

Known as: Anti-Progestin, Anti-progesterones, antiprogestin 
A substance that prevents cells from making or using progesterone (a hormone that plays a role in the menstrual cycle and pregnancy). Antiprogestins… 
National Institutes of Health

Papers overview

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Highly Cited
1999
Highly Cited
1999
Synergistic role of nitric oxide and progesterone during the establishment of pregnancy in the rat.
Successful pregnancy is strictly dependent on the trophoblast-decidual interaction and on an adequate blood supply to the… 
Highly Cited
1998
Highly Cited
1998
Effects of long-term low-dose mifepristone on reproductive function in women.
Low-dose antiprogestin administration has been proposed as a new contraceptive modality to interference with endometrial… 
Highly Cited
1992
Highly Cited
1992
Ligand-dependent conformational changes in the progesterone receptor are necessary for events that follow DNA binding.
Hormones and antihormones induce related, but distinct, conformational changes in the progesterone receptor [Allan, G. F., Leng… 
Highly Cited
1992
Highly Cited
1992
Technetium- and rhenium-labeled progestins: synthesis, receptor binding and in vivo distribution of an 11 beta-substituted progestin labeled with technetium-99 and rhenium-186.
In an effort to develop radiopharmaceuticals useful for the diagnostic imaging of steroid receptor-positive breast tumors, we… 
Highly Cited
1991
Highly Cited
1991
Estrogen-inducible progesterone receptor in primary cultures of rat glial cells.
Highly Cited
1988
Highly Cited
1988
Effects of progestins on sexual behaviour in castrated lizards (Cnemidophorus inornatus).
In many male vertebrates, androgens stimulate, while progesterone inhibits, sexual behaviour. Testicular androgens also control… 
Review
1987
Review
1987
Integration of the effects of estradiol and progesterone in the modulation of gonadotropin secretion.
Highly Cited
1987
Highly Cited
1987
Reversal of the antitumor effects of tamoxifen by progesterone in the 7,12-dimethylbenzanthracene-induced rat mammary carcinoma model.
Coadministration of progesterone (4 mg/day) opposed the antitumor activity of tamoxifen (100 micrograms/day) in rats bearing 7,12… 
Highly Cited
1987
Highly Cited
1987
The progesterone antagonist RU 486. A potential new contraceptive agent.
Abstract Since progesterone supports endometrial nidation of the fertilized ovum, a progesterone antagonist would theoretically… 
Highly Cited
1983
Highly Cited
1983
Binding of the anti-progestin RU-486 to rat ovary steroid receptors.
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