Proflavine

Translocation requires large-scale movements of ribosome-bound tRNAs. Using tRNAs that are proflavin labeled and single-turnover… (More)

The structural basis of simultaneous binding of two or more different drugs by any multidrug-binding protein is unknown and also… (More)

The genes tehAB located at 32.3 min on the Escherichia coli chromosome were initially identified by their ability to mediate… (More)

Conformational transitions of Phe-tRNA(Phe) that take place during elongation factor Tu (EF-Tu)-dependent binding to the A site… (More)

The specific recognition of DNA modifications by repair endonucleases was used to characterize the DNA damage induced by… (More)

A molecular model has been derived for the intercalation of proflavine into the CpG site of the decamer duplex of d(GATACGATAC… (More)

Frequencies of spontaneous and proflavine-induced frameshift mutations increased dramatically as a function of the number of… (More)

The antitumor agent amsacrine, 4'-(9-acridinylamino)methanesulfon-m-anisidide (m-AMSA), when bound to double-stranded DNA… (More)

A new method is described that uses the fluorochrome primulin and epifluorescence microscopy for the enumeration of heterotrophic… (More)

* Report of work supported by the U.S. Public Health Service, grants no. RG-3977, RG-5143, and A-3102. We wish to acknowledge the… (More)