Prodine
National Institutes of Health
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Several different classes of opiates such as PET (7-alpha-(1-Hydroxy-1-methyl-3-phenylpropyl)-6,14-endo-ethenotetra…
The (-)- and (+)-isomers of the cis- and trans-Ph/Me 1-(1-phenyl-2-methylcyclohexyl)piperidines have been synthesized and the…
The two optical isomers of 1-[3-(p-fluorobenzoyl) propyl]-3-methyl-4-phenyl-4-propionoxypiperidine (FPP) were obtained by…
The conformational preferences of phenylmorphan have been determined by the MM2 (Molecular Mechanics II) program using full…
Analogs of the prodine analgesics were prepared and tested for analgesic activity. A good correlation seems to exist between the…
The receptor binding affinities of some diastereoisomeric prodine analgoues have been compared with their analgetic activities…
2,4,5-Trimethylpyrrole-3-carboxylic acid esters of tropanols and related monocyclic amino alcohols were synthesized and evaluated…
Opical antipodes of the axial phenyl analgetic, alpha-promedol hydrochloride (3), were prepared and the absolute stereochemistry…