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Prions

Known as: prion proteins, prion protein, Prions [Chemical/Ingredient] 
Small proteinaceous infectious particles which resist inactivation by procedures that modify NUCLEIC ACIDS and contain an abnormal isoform of a… 
National Institutes of Health

Related topics

Related topics

22 relations
In BloodPRND genePRNP genePRNT gene

Narrower (7)

PRND protein, humanPrP 27-30 ProteinPrion ProteinsPrnd protein, mouse

Broader (1)

Viroids

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2008
Review
2008
The prion's elusive reason for being.
The protein-only hypothesis posits that the infectious agent causing transmissible spongiform encephalopathies consists of… 
Highly Cited
2004
Highly Cited
2004
Protein-only transmission of three yeast prion strains
Key questions regarding the molecular nature of prions are how different prion strains can be propagated by the same protein and… 
Review
2004
Review
2004
Emerging principles of conformation-based prion inheritance.
The prion hypothesis proposes that proteins can act as infectious agents. Originally formulated to explain transmissible… 
Highly Cited
2003
Highly Cited
2003
A quantitative, highly sensitive cell-based infectivity assay for mouse scrapie prions
Prions are usually quantified by bioassays based on intracerebral inoculation of mice that are slow, imprecise, and costly. We… 
Highly Cited
2003
Highly Cited
2003
Balancing Selection at the Prion Protein Gene Consistent with Prehistoric Kurulike Epidemics
Kuru is an acquired prion disease largely restricted to the Fore linguistic group of the Papua New Guinea Highlands, which was… 
Review
2002
Review
2002
Neuroinflammation in Alzheimer's disease and prion disease
Alzheimer's disease (AD) and prion disease are characterized neuropathologically by extracellular deposits of Aβ and PrP amyloid… 
Highly Cited
2002
Highly Cited
2002
Stress‐inducible protein 1 is a cell surface ligand for cellular prion that triggers neuroprotection
Prions are composed of an isoform of a normal sialoglycoprotein called PrPc, whose physiological role has been under… 
Highly Cited
2001
Highly Cited
2001
Prions Affect the Appearance of Other Prions The Story of [PIN+]
Highly Cited
1997
Highly Cited
1997
Genetic and environmental factors affecting the de novo appearance of the [PSI+] prion in Saccharomyces cerevisiae.
It has previously been shown that yeast prion [PSI+] is cured by GuHCl, although reports on reversibility of curing were… 
Highly Cited
1996
Highly Cited
1996
Support for the Prion Hypothesis for Inheritance of a Phenotypic Trait in Yeast
A cytoplasmically inherited genetic element in yeast, [PSI+], was confirmed to be a prionlike aggregate of the cellular protein… 
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