PrP 27-30 Protein

Known as: PrP 27-30 Protein [Chemical/Ingredient], Scrapie Associated Fibril Protein, Scrapie PrP 27-30 Protein 
Protease-resistant core of PrPSc, the abnormal isoform of PRION PROTEINS. PrP 27-30 is produced by limited proteolysis of the N-terminus of PrPSc.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1967-2017
0102019672017

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Highly Cited
2013
Highly Cited
2013
Tauopathies, including Alzheimer's disease (AD) and frontotemporal lobar degeneration with tau pathologies, are neurodegenerative… (More)
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Highly Cited
2005
Highly Cited
2005
Prions are unconventional infectious agents responsible for transmissible spongiform encephalopathy (TSE) diseases. They are… (More)
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Highly Cited
1993
Highly Cited
1993
Mice, homozygous for prion protein (PrP) gene ablation (Prn-p0/0), develop normally and remain well > 500 days after inoculation… (More)
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Highly Cited
1992
Highly Cited
1992
Infectious scrapie prions are composed largely, if not entirely, of an abnormal isoform of the prion protein (PrP) which is… (More)
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Highly Cited
1992
Highly Cited
1992
Scrapie is characterized by the accumulation of a protease-resistant isoform of the prion protein PrPSc. Limited proteolysis and… (More)
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Highly Cited
1991
Highly Cited
1991
A protease-resistant form of the protein PrP (PrP-res) accumulates in tissues of mammals infected with scrapie, Creutzfeldt-Jakob… (More)
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Highly Cited
1991
Highly Cited
1991
SC-35 is a non-snRNP spliceosome component that is specifically recognized by the anti-spliceosome monoclonal antibody alpha SC… (More)
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Highly Cited
1986
Highly Cited
1986
Scrapie is a slow degenerative encephalopathy of animals caused by unusual infectious particles termed prions. A cDNA encoding… (More)
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Highly Cited
1985
Highly Cited
1985
A clone encoding PrP 27-30, the major protein in purified preparations of scrapie agent, was selected from a scrapie-infected… (More)
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1985
1985
The major scrapie prion protein, designated PrP 27-30, exhibited both charge and size heterogeneity after purification from… (More)
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