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PrP 27-30 Protein

Known as: PrP 27-30 Protein [Chemical/Ingredient], Scrapie Associated Fibril Protein, Scrapie PrP 27-30 Protein 
Protease-resistant core of PrPSc, the abnormal isoform of PRION PROTEINS. PrP 27-30 is produced by limited proteolysis of the N-terminus of PrPSc.
National Institutes of Health

Related topics

Related topics

9 relations
In BloodProcess of secretionagonistsantagonists & inhibitors

Broader (1)

Prions

Papers overview

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Highly Cited
2012
Highly Cited
2012
Antiparallel β-sheet architecture in Iowa-mutant β-amyloid fibrils
Wild-type, full-length (40- and 42-residue) amyloid β-peptide (Aβ) fibrils have been shown by a variety of magnetic resonance… 
Highly Cited
2001
Highly Cited
2001
Imbalance of antioxidant defense in mice lacking cellular prion protein.
Highly Cited
1994
Highly Cited
1994
Binding of the protease-sensitive form of PrP (prion protein) to sulfated glycosaminoglycan and congo red [corrected]
Congo red and certain sulfated glycans are potent inhibitors of protease-resistant PrP accumulation in scrapie-infected cells… 
Highly Cited
1994
Highly Cited
1994
Perichromatin fibrils are in situ forms of nascent transcripts.
Highly Cited
1993
Highly Cited
1993
Synthetic peptides homologous to prion protein residues 106-147 form amyloid-like fibrils in vitro.
Gerstmann-Sträussler-Scheinker disease (GSS) is a prion-related encephalopathy pathologically characterized by massive deposition… 
Highly Cited
1991
Highly Cited
1991
Associations between distinct pre‐mRNA splicing components and the cell nucleus.
SC‐35 is a non‐snRNP spliceosome component that is specifically recognized by the anti‐spliceosome monoclonal antibody alpha SC… 
Highly Cited
1987
Highly Cited
1987
Changes in the localization of brain prion proteins during scrapie infection
Prion proteins (PrP) were localized in the brains of normal and scrapie-infected hamsters by immunohistochemistry and Western… 
Highly Cited
1986
Highly Cited
1986
The major polypeptide of scrapie‐associated fibrils (SAF) has the same size, charge distribution and N‐terminal protein sequence as predicted for the normal brain protein (PrP).
Scrapie‐associated fibrils (SAF) are unique structures characteristic of the group of unconventional slow infections which… 
Highly Cited
1985
Highly Cited
1985
Scrapie PrP 27-30 is a sialoglycoprotein
The major scrapie prion protein, designated PrP 27-30, exhibited both charge and size heterogeneity after purification from… 
Highly Cited
1977
Highly Cited
1977
Characteristics of a short incubation model of scrapie in the golden hamster.
Repeated passage of the "Chandler" strain of scrapie in female golden hamsters using the intracerebral route of inoculation… 
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