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Primase Polypeptide 1

Known as: EC 2.7.7.-, Primase p48 Subunit, Primase p49 Subunit 
DNA primase small subunit (420aa, ~50 kDa) is encoded by the human PRIM1 gene. This protein is involved in the biosynthesis of RNA primers for the… Expand
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
To newly identify loci for age at natural menopause, we carried out a meta-analysis of 22 genome-wide association studies (GWAS… Expand
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2008
2008
A homology search of a public database revealed that Spodoptera litura nucleopolyhedrovirus (SpltNPV) possesses two putative… Expand
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2007
2007
Baculoviruses induce widespread apoptosis in invertebrates. To better understand the pathways by which these DNA viruses trigger… Expand
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2005
2005
In addition to its hemostatic functions, factor (F)VIIa exhibits cell proliferative properties as seen in angiogenesis and tumor… Expand
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Highly Cited
2002
Highly Cited
2002
Caspases play a critical role in the execution of metazoan apoptosis and are thus attractive therapeutic targets for apoptosis… Expand
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2002
2002
Two antiapoptotic types of genes, iap and p35, were found in baculoviruses. P35 is a 35-kDa protein that can suppress apoptosis… Expand
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2002
2002
This study characterized the ability of a new member of the p35 family, p49, to inhibit a number of mammalian and insect caspases… Expand
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Highly Cited
1998
Highly Cited
1998
NK cells display several killer inhibitory receptors (KIR) specific for different alleles of MHC class I molecules. A family of… Expand
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Review
1998
Review
1998
Recent studies indicate that calpain, a cytosolic Ca2+-dependent protease, constitutes a large family comprising ubiquitous… Expand
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1992
1992
Neutrophils stimulated with 4 beta-phorbol 12-myristate 13-acetate (PMA) release large quantities of superoxide (O2-) and exhibit… Expand
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