Primary malignant neoplasm of brain

Known as: Malignant Primary Brain Neoplasm, Malignant Primary Brain Neoplasms, Brain Neoplasms, Primary Malignant 
A malignant neoplasm that arises from the brain. Representative examples include anaplastic astrocytoma, glioblastoma, and lymphoma.
National Institutes of Health

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Benign neoplasm of brain, unspecifiedBrainCentral Nervous SystemNeoplastic Cell
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Brain Neoplasms

Papers overview

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Review
2015
Review
2015
Cancer stem cells in glioblastoma.
Tissues with defined cellular hierarchies in development and homeostasis give rise to tumors with cellular hierarchies… (More)
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Highly Cited
2012
Highly Cited
2012
Dedifferentiation of neurons and astrocytes by oncogenes can induce gliomas in mice.
Glioblastoma multiforme (GBM) is the most common and aggressive malignant primary brain tumor in humans. Here we show that… (More)
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Highly Cited
2012
Highly Cited
2012
Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas
Mutations in the critical chromatin modifier ATRX and mutations in CIC and FUBP1, which are potent regulators of cell growth… (More)
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Review
2006
Review
2006
Epidemiology and molecular pathology of glioma
Gliomas account for almost 80% of primary malignant brain tumors, and they result in more years of life lost than do any other… (More)
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Review
2002
Review
2002
Management of brain metastases
Brain metastases occur in 20–40 % of patients with cancer and their frequency has increased over time. Lung, breast and skin… (More)
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Highly Cited
1999
Highly Cited
1999
The conditional probability of survival of patients with primary malignant brain tumors: surveillance, epidemiology, and end results (SEER) data.
BACKGROUND Five-year survival estimates in standard cancer reports provide a general description of disease outcome that is… (More)
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Review
1999
Review
1999
New treatment strategies for malignant gliomas.
Although survival in patients with malignant gliomas remains limited, there is renewed optimism with the emergence of novel… (More)
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Highly Cited
1998
Highly Cited
1998
Trends in reported incidence of primary malignant brain tumors in children in the United States.
BACKGROUND The reported incidence of primary malignant brain tumors among children in the United States increased by 35% during… (More)
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Highly Cited
1998
Highly Cited
1998
Survival rates in patients with primary malignant brain tumors stratified by patient age and tumor histological type: an analysis based on Surveillance, Epidemiology, and End Results (SEER) data…
OBJECT The authors present population-based survival rate estimates for patients with malignant primary brain tumors based on an… (More)
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Highly Cited
1982
Highly Cited
1982
Human central nervous system distribution of cis-diamminedichloroplatinum and use as a radiosensitizer in malignant brain tumors.
The human central nervous system pharmacology of c/'sdiamminedichloroplatinum (CDDP) was studied, and trials were initiated of… (More)
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