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Pragmatic Clinical Trials as Topic

Known as: Trials, Pragmatic, Pragmatic Trials, Trials, Practical Clinical 
Works about randomized clinical trials that compare interventions in clinical settings and which look at a range of effectiveness outcomes and… 
National Institutes of Health

Related topics

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4 relations
Comparative Effectiveness ResearchPragmatic Clinical Triallegislation & jurisprudencestandards characteristics

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2019
Highly Cited
2019
The importance of adherence in tuberculosis treatment clinical trials and its relevance in explanatory and pragmatic trials
Andrew Vernon and co-authors discuss adherence to therapy and its measurement in tuberculosis treatment trials. 
Highly Cited
2017
Highly Cited
2017
Real-world Data for Clinical Evidence Generation in Oncology.
Conventional cancer clinical trials can be slow and costly, often produce results with limited external validity, and are… 
Highly Cited
2016
Highly Cited
2016
A Novel Brief Therapy for Patients Who Attempt Suicide: A 24-months Follow-Up Randomized Controlled Study of the Attempted Suicide Short Intervention Program (ASSIP)
Background Attempted suicide is the main risk factor for suicide and repeated suicide attempts. However, the evidence for follow… 
Highly Cited
2014
Highly Cited
2014
Informed consent for pragmatic trials--the integrated consent model.
The authors argue that informed consent is ethically necessary in pragmatic trials that randomly assign individual patients to… 
Highly Cited
2014
Highly Cited
2014
Obtaining real-world evidence: the Salford Lung Study
We need to assess clinical treatments in real-life settings outside of randomised controlled trials (RCTs). Pragmatic RCT (pRCT… 
Highly Cited
2014
Highly Cited
2014
Explanatory trials versus pragmatic trials
Researchers assessed the effectiveness of weekly delivery of low dose high frequency therapeutic ultrasound in conjunction with… 
Review
2013
Review
2013
Importance of mixed methods in pragmatic trials and dissemination and implementation research.
Review
2010
Review
2010
Disorder-specific psychosocial interventions for bipolar disorder--a systematic review of the evidence for mental health nursing practice.
Review
2008
Review
2008
Evidence-based medicine, systematic reviews, and guidelines in interventional pain management: Part 2: Randomized controlled trials.
Evidence-based medicine (EBM) is a shift in medical paradigms and about solving clinical problems, acknowledging that intuition… 
Review
2007
Review
2007
Pragmatic trials in primary care. Methodological challenges and solutions demonstrated by the DIAMOND-study
BackgroundPragmatic randomised controlled trials are often used in primary care to evaluate the effect of a treatment strategy… 
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