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Potassium Channel Openers [MoA]
Known as:
Potassium Channel Activators
, Potassium Channel Openers
National Institutes of Health
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Related topics
Related topics
2 relations
Potassium Channel Opener [EPC]
ezogabine
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Synthesis and activity on rat aorta rings and rat pancreatic beta-cells of ring-opened analogues of benzopyran-type potassium channel activators.
S. Khelili
,
Xavier Florence
,
+6 authors
B. Pirotte
Bioorganic & Medicinal Chemistry
2008
Corpus ID: 43264866
2002
2002
The novel diazoxide analog 3-isopropylamino-7-methoxy-4H-1,2,4-benzothiadiazine 1,1-dioxide is a selective Kir6.2/SUR1 channel opener.
M. Dabrowski
,
F. Ashcroft
,
+5 authors
P. Wahl
Diabetes
2002
Corpus ID: 21572410
ATP-sensitive K(+) (K(ATP)) channels are activated by a diverse group of compounds known as potassium channel openers (PCOs…
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2002
2002
6-Sulfonylchromenes as highly potent K(ATP)-channel openers.
E. Salamon
,
R. Mannhold
,
H. Weber
,
H. Lemoine
,
W. Frank
Journal of Medicinal Chemistry
2002
Corpus ID: 882624
We synthesized K(ATP)-channel openers (KCOs) composed of the 4-pyridonechromene moiety of bimakalim (1) and a variety of sulfonyl…
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1999
1999
Potassium channel openers antagonize the effects of class III antiarrhythmic agents in canine Purkinje fiber action potentials. Implications for prevention of proarrhythmia induced by class III…
M. Kondo
,
T. Tsutsumi
,
S. Mashima
Japanese Heart Journal
1999
Corpus ID: 28923433
We studied the effects of potassium channel openers (PCOs) on frequency dependent prolongations of action potential duration (APD…
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1997
1997
Potassium channel opener-augmented cardioplegia: protection of myocyte contractility with chronic left ventricular dysfunction.
B. Dorman
,
L. Hebbar
,
M. J. Clair
,
Robert B. Hinton
,
Raymond C. Roy
,
F. Spinale
Circulation
1997
Corpus ID: 22387151
BACKGROUND An increased number of patients with preexisting left ventricular (LV) dysfunction and congestive heart failure (CHF…
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1997
1997
Hyperpolarized cardioplegic arrest with nicorandil: advantages over other potassium channel openers.
A. Jayawant
,
J. Lawton
,
P. Hsia
,
R. Damiano
Circulation
1997
Corpus ID: 31302040
BACKGROUND Our laboratory has demonstrated that the potassium channel openers (PCOs) aprikalim and pinacidil are effective…
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1996
1996
N-aryl-3,3,3-trifluoro-2-hydroxy-2-methylpropanamides: KATP potassium channel openers. Modifications on the western region.
C. Ohnmacht
,
K. Russell
,
+28 authors
K. Neilson
Journal of Medicinal Chemistry
1996
Corpus ID: 25816020
A subset of antiandrogen compounds, the N-aryl-3,3,3-trifluoro-2-hydroxy-2-methylpropanamides 1, were found to activate ATP…
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Review
1995
Review
1995
Ischemic myocardial cell protection conferred by the opening of ATP-sensitive potassium channels
I. Cavero
,
Y. Djellas
,
J. Guillon
Cardiovascular Drugs and Therapy
1995
Corpus ID: 12291546
SummaryThe responses of the cardiac myocyte to a potentially injurious ischemic stress are multiple. The opening of the ATP…
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1990
1990
K(+)-channel openers for relaxation of isolated penile erectile tissue from rabbit.
F. Holmquist
,
K. Andersson
,
M. Fovaeus
,
H. Hedlund
Journal of Urology
1990
Corpus ID: 23447470
1990
1990
Effects of pinacidil on isolated human corpus cavernosum penis.
F. Holmquist
,
K. Andersson
,
H. Hedlund
Acta Physiologica Scandinavica
1990
Corpus ID: 22439326
Intracavernous injection of vasoactive agents causing vasodilatation is widely recognized in the diagnosis and treatment of…
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