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Polymyxins

Known as: Polymyxin, Polymyxins [Chemical/Ingredient] 
Basic lipopeptide antibiotic group obtained from Bacillus polymyxa. They affect the cell membrane by detergent action and may cause neuromuscular and… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
Carbapenems are considered as last-resort antibiotics for the treatment of infections caused by multidrug-resistant Gram-negative… Expand
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Review
2019
Review
2019
ABSTRACT The increase in antibiotic resistance is a global concern for human and animal health. Resistant microorganisms can… Expand
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Review
2018
Review
2018
  • T. Iba, J. Levy
  • Journal of thrombosis and haemostasis : JTH
  • 2018
  • Corpus ID: 28784562
The inflammatory response and the activation of coagulation are two important responses in a host's defense against infection… Expand
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Highly Cited
2016
Highly Cited
2016
  • Yi-yun Liu, Yang Wang, +17 authors J. Shen
  • The Lancet. Infectious diseases
  • 2016
  • Corpus ID: 206154294
BACKGROUND Until now, polymyxin resistance has involved chromosomal mutations but has never been reported via horizontal gene… Expand
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Review
2008
Review
2008
SUMMARY The global emergence of multidrug-resistant gram-negative bacilli has spurred a renewed interest in polymyxins. Once… Expand
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Review
2006
Review
2006
The increasing trend of carbapenem resistance in Acinetobacter baumannii worldwide is a concern since it limits drastically the… Expand
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Review
2005
Review
2005
The emergence of multidrug-resistant gram-negative bacteria and the lack of new antibiotics to combat them have led to the… Expand
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Highly Cited
1998
Highly Cited
1998
Antimicrobial peptides are distributed throughout the animal kingdom and are a key component of innate immunity. Salmonella… Expand
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Review
1977
Review
1977
The general mechanism for the antibiotic activities of the polymyxins and octapeptins has been elucidated by research using a… Expand
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Highly Cited
1976
Highly Cited
1976
Abstract The cationic polypeptide polymyxin B, has been demonstrated to form a stable molecular complex with the lipid A region… Expand
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