Polymyxins

Known as: Polymyxin, Polymyxins [Chemical/Ingredient] 
Basic lipopeptide antibiotic group obtained from Bacillus polymyxa. They affect the cell membrane by detergent action and may cause neuromuscular and… (More)
National Institutes of Health

Papers overview

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Review
2016
Review
2016
INTRODUCTION Antimicrobial peptides (AMPs) represent the large group of endogenous compounds widely distributed in nature. Due to… (More)
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Highly Cited
2015
Highly Cited
2015
BACKGROUND Until now, polymyxin resistance has involved chromosomal mutations but has never been reported via horizontal gene… (More)
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Review
2010
Review
2010
Polymyxins act by binding to lipid A moiety of the bacterial lipopolysaccharide and subsequently disintegrating the bacterial… (More)
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Review
2010
Review
2010
Tony Velkov,* Philip E. Thompson, Roger L. Nation, and Jian Li* School of Medicine, Deakin University, Pigdons Road, Geelong 3217… (More)
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Review
2008
Review
2008
The global emergence of multidrug-resistant gram-negative bacilli has spurred a renewed interest in polymyxins. Once discarded… (More)
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Review
2005
Review
2005
The emergence of multidrug-resistant gram-negative bacteria and the lack of new antibiotics to combat them have led to the… (More)
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Highly Cited
2005
Highly Cited
2005
OBJECTIVES To describe the molecular epidemiology of carbapenem-resistant Klebsiella pneumoniae in Brooklyn, NY and assess the in… (More)
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Highly Cited
2003
Highly Cited
2003
The two-component regulatory system PhoP-PhoQ of Pseudomonas aeruginosa regulates resistance to cationic antimicrobial peptides… (More)
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Highly Cited
1998
Highly Cited
1998
Antimicrobial peptides are distributed throughout the animal kingdom and are a key component of innate immunity. Salmonella… (More)
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Review
1977
Review
1977
The general mechanism for the antibiotic activities of the polymyxins and octapeptins has been elucidated by research using a… (More)
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