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NAB 7061 peptide

Known as: NAB7061 
 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Polymyxins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Polymyxin Derivatives that Sensitize Gram-Negative Bacteria to Other Antibiotics
Polymyxins (polymyxin B (PMB) and polymyxin E (colistin)) are cyclic lipodecapeptide antibiotics, highly basic due to five free… Expand
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2014
2014
Old and Novel Polymyxins Against Serious Gram-Negative Infections
Polymyxins (polymyxin B and colistin) are bactericidal pentacationic cyclic lipodecapeptides that act specifically on Gram… Expand
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Review
2013
Review
2013
The renaissance of polymyxins.
Polymyxins are polypeptide antibiotics, with a primary effect of membrane damaging due to their selective binding to the… Expand
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2012
2012
Novel polymyxin derivatives are less cytotoxic than polymyxin B to renal proximal tubular cells
The emergence of very multiresistant Gram-negative bacterial strains has reinstated polymyxins (polymyxin B, colistin… Expand
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Highly Cited
2010
Highly Cited
2010
A novel polymyxin derivative that lacks the fatty acid tail and carries only three positive charges has strong synergism with agents excluded by the intact outer membrane.
Polymyxins are cationic lipopeptides (five cationic charges) and the last resort for the treatment of serious Gram-negative… Expand
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2010
2010
Novel polymyxin derivatives are effective in treating experimental Escherichia coli peritoneal infection in mice.
OBJECTIVES Novel synthetic polymyxin derivatives including NAB737 and NAB739 are as effective as polymyxin B in vitro against the… Expand
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2010
2010
Structure–activity studies on novel polymyxin derivatives that carry only three positive charges
Polymyxin B and colistin are pentacationic lipopeptides that possess a cyclic heptapeptide portion, a linear tripeptide portion… Expand
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2010
2010
Susceptibility of carbapenemase-producing strains of Klebsiella pneumoniae and Escherichia coli to the direct antibacterial activity of NAB739 and to the synergistic activity of NAB7061 with…
OBJECTIVES To determine the susceptibility of carbapenemase-producing strains of Klebsiella pneumoniae and Escherichia coli to… Expand
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Highly Cited
2008
Highly Cited
2008
Novel polymyxin derivatives carrying only three positive charges are effective antibacterial agents.
The lack of novel antibiotics against gram-negative bacteria has reinstated polymyxins as the drugs of last resort to treat… Expand
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