Polymyxin B

Known as: Polymyxine B, Polimixina B, b polymyxin 
A mixture of the polypeptides polymyxins B1 and B2, both obtained from Bacillus polymyxa strains, with antimicrobial activity. Polymyxin B exerts its… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1948-2017
010020019482016

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Highly Cited
2009
Highly Cited
2009
CONTEXT Polymyxin B fiber column is a medical device designed to reduce blood endotoxin levels in sepsis. Gram-negative-induced… (More)
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2008
2008
BACKGROUND Although not much pharmacokinetic knowledge is available, polymyxin B is increasingly used for treatment of infections… (More)
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Highly Cited
2006
Highly Cited
2006
In total, 54 731 Gram-negative bacilli isolated worldwide between 2001 and 2004 from diverse sites of infection were tested for… (More)
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Highly Cited
2005
Highly Cited
2005
OBJECTIVES To describe the molecular epidemiology of carbapenem-resistant Klebsiella pneumoniae in Brooklyn, NY and assess the in… (More)
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2005
2005
Despite limited data, polymyxin B (PB) is increasingly used clinically as the last therapeutic option for multidrug-resistant… (More)
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Highly Cited
2003
Highly Cited
2003
The two-component regulatory system PhoP-PhoQ of Pseudomonas aeruginosa regulates resistance to cationic antimicrobial peptides… (More)
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Highly Cited
2001
Highly Cited
2001
The retinoblastoma tumour suppressor (Rb) pathway is believed to have a critical role in the control of cellular proliferation by… (More)
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Highly Cited
1999
Highly Cited
1999
The life-threatening complications of sepsis in humans are elicited by infection with Gram-negative as well as Gram-positive… (More)
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Highly Cited
1986
Highly Cited
1986
Recombinant human tumor necrosis factor (rTNF alpha) injected intravenously into rabbits produces a rapid-onset, monophasic fever… (More)
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1974
1974
The limulus gelation assay was utilized to investigate endotoxin inactivation by a number of antibiotics in vitro. Endotoxin… (More)
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