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Polymerase

Encoded by Polymerase Genes, Polymerase enzymes catalyze polymerization reactions, especially of nucleotides to polynucleotides. (NCI)
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Eukaryotes use distinct polymerases for leading- and lagging-strand replication, but how they target their respective strands is… Expand
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Highly Cited
2013
Highly Cited
2013
DNA polymerase (pol) β is a model polymerase involved in gap-filling DNA synthesis utilizing two metals to facilitate nucleotidyl… Expand
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Highly Cited
2009
Highly Cited
2009
High-throughput genomics and the emerging field of synthetic biology demand ever more convenient, economical, and efficient… Expand
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Highly Cited
2009
Highly Cited
2009
DNA-damage-induced SOS mutations arise when Escherichia coli DNA polymerase (pol) V, activated by a RecA nucleoprotein filament… Expand
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Highly Cited
2008
Highly Cited
2008
Human DNA polymerase theta (pol θ or POLQ) is a proofreading-deficient family A enzyme implicated in translesion synthesis (TLS… Expand
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Highly Cited
2007
Highly Cited
2007
Cells use transcription-coupled repair (TCR) to efficiently eliminate DNA lesions such as ultraviolet light–induced cyclobutane… Expand
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Highly Cited
2005
Highly Cited
2005
Epstein-Barr virus (EBV or HHV4), a member of the human herpesvirus (HHV) family, has recently been shown to encode microRNAs… Expand
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Tenofovir (TDF) is an adenosine nucleotide analogue that has been approved for the treatment of HIV-1 infection. It… Expand
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Highly Cited
2001
Highly Cited
2001
The human positive transcription elongation factor P-TEFb, consisting of a CDK9/cyclin T1 heterodimer, functions as both a… Expand
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Highly Cited
2000
Highly Cited
2000
Small DNA lesions such as oxidized or alkylated bases are repaired by the base excision repair (BER) pathway. BER includes… Expand
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