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Fruiting body formation by Bacillus subtilis
- S. Branda, J. Gónzalez-Pastor, S. Ben-Yehuda, R. Losick, R. Kolter
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 25 September 2001
Spore formation by the bacterium Bacillus subtilis has long been studied as a model for cellular differentiation, but predominantly as a single cell. When analyzed within the context of highly… Expand
A widely conserved bacterial cell division protein that promotes assembly of the tubulin-like protein FtsZ.
Cell division in bacteria is mediated by the tubulin-like protein FtsZ, which assembles into a structure known as the Z ring at the future site of cytokinesis. We report the discovery of a… Expand
A master regulator for biofilm formation by Bacillus subtilis
- D. Kearns, Frances Chu, S. Branda, R. Kolter, R. Losick
- Biology, Medicine
- Molecular microbiology
- 2 December 2004
Wild strains of Bacillus subtilis are capable of forming architecturally complex communities of cells known as biofilms. Critical to biofilm formation is the eps operon, which is believed to be… Expand
High- and low-threshold genes in the Spo0A regulon of Bacillus subtilis.
The master regulator for entry into sporulation in Bacillus subtilis is the response regulator Spo0A, which directly governs the expression of about 121 genes. Using cells in which the synthesis of… Expand
Molecular genetics of sporulation in Bacillus subtilis.
The process of sporulation in the bacterium Bacillus subtilis proceeds through a well-defined series of morphological stages that involve the conversion of a growing cell into a two-cell-chamber… Expand
Construction of a cloning site near one end of Tn917 into which foreign DNA may be inserted without affecting transposition in Bacillus subtilis or expression of the transposon-borne erm gene.
A 1.3-kb restriction fragment carrying a cat gene derived from Staphylococcus aureus was inserted by ligation in both possible orientations into a HpaI restriction site located less than 300 bp from… Expand
The Spo0A regulon of Bacillus subtilis
The master regulator for entry into sporulation in Bacillus subtilis is the DNA‐binding protein Spo0A, which has been found to influence, directly or indirectly, the expression of over 500 genes… Expand
Chromosome and Low Copy Plasmid Segregation in E. coli: Visual Evidence for Distinct Mechanisms
We have investigated DNA segregation in E. coli by inserting multiple lac operator sequences into the chromosome near the origin of replication (oriC), in the hisC gene, a terminus marker, and into… Expand
Cannibalism by Sporulating Bacteria
Spore formation by the bacterium Bacillus subtilis is an elaborate developmental process that is triggered by nutrient limitation. Here we report that cells that have entered the pathway to sporulate… Expand
Control of cell fate by the formation of an architecturally complex bacterial community.
Bacteria form architecturally complex communities known as biofilms in which cells are held together by an extracellular matrix. Biofilms harbor multiple cell types, and it has been proposed that… Expand