• Publications
  • Influence
Cajal bodies: the first 100 years.
  • J. Gall
  • Biology, Medicine
  • Annual review of cell and developmental biology
  • 2000
Cajal bodies are small nuclear organelles first described nearly 100 years ago by Ramón y Cajal in vertebrate neural tissues. They have since been found in a variety of animal and plant nuclei,Expand
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A conserved double-stranded RNA-binding domain.
We have identified a double-stranded (ds)RNA-binding domain in each of two proteins: the product of the Drosophila gene staufen, which is required for the localization of maternal mRNAs, and aExpand
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Efficient gene targeting in Drosophila by direct embryo injection with zinc-finger nucleases
We report very high gene targeting frequencies in Drosophila by direct embryo injection of mRNAs encoding specific zinc-finger nucleases (ZFNs). Both local mutagenesis via nonhomologous end joiningExpand
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Assembly of the nuclear transcription and processing machinery: Cajal bodies (coiled bodies) and transcriptosomes.
We have examined the distribution of RNA transcription and processing factors in the amphibian oocyte nucleus or germinal vesicle. RNA polymerase I (pol I), pol II, and pol III occur in the CajalExpand
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A tandemly repeated sequence at the termini of the extrachromosomal ribosomal RNA genes in Tetrahymena.
Abstract The extrachromosomal genes coding for ribosomal RNA (rDNA) in the ciliated protozoan Tetrahymena thermophila were studied with respect to sequences occurring at their termini. The linearExpand
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The Cajal body and histone locus body.
The Cajal body (CB) is a nuclear organelle present in all eukaryotes that have been carefully studied. It is identified by the signature protein coilin and by CB-specific RNAs (scaRNAs). CBs containExpand
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The Drosophila melanogaster Cajal body
Cajal bodies (CBs) are nuclear organelles that are usually identified by the marker protein p80-coilin. Because no orthologue of coilin is known in Drosophila melanogaster, we identified D.Expand
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Chromosomal Localization of Mouse Satellite DNA
Hybridization of radioactive nucleic acids with the DNA of cytological preparations shows that the sequences of mouse satellite DNA are located in the centromeric heterochromatin of the mouseExpand
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Formation and detection of RNA-DNA hybrid molecules in cytological preparations.
  • J. Gall, M. Pardue
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 1 June 1969
A technique is described for forming molecular hybrids between RNA in solution and the DNA of intact cytological preparations. Cells in a conventional tissue squash are immobilized under a thin layerExpand
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The centennial of the Cajal body
  • J. Gall
  • Biology, Medicine
  • Nature Reviews Molecular Cell Biology
  • 1 December 2003
Exactly 100 years ago, the Spanish neurobiologist Santiago Ramón y Cajal described a new organelle in the nuclei of vertebrate neurons. Now called the Cajal body, this organelle occurs in many cellExpand
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