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Polyketides
Known as:
Polyketides [Chemical/Ingredient]
Natural compounds containing alternating carbonyl and methylene groups (beta-polyketones), bioenergenetically derived from repeated condensation of…
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National Institutes of Health
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In Blood
agonists
antagonists & inhibitors
chemical synthesis
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JBIR-85
Ketides
PM050489
PM060184
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Biosynthesis: "Aromatic Polyketides, Isoprenoids, Alkaloids"
F. Leeper
,
J. Vederas
2010
Corpus ID: 83384085
Biosynthesis of Aromatic Polyketides.- Cyclization Enzymes in the Biosynthesis of Monoterpenes, Sesquiterpenes, and Diterpenes…
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2010
2010
Handbook of Pharmaceutical Natural Products
G. Brahmachari
2010
Corpus ID: 92892817
PREFACE A Abacopternis A-D --- Azoxybacilin B Ballotenic acid and ballodiolic acid --- 7-n-Butyl-6,8-dihydroxy-3(R)-pent-11…
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2008
2008
Sequential asymmetric polyketide heterocyclization catalyzed by a single cytochrome P450 monooxygenase (AurH).
Martin E. A. Richter
,
Nelly Traitcheva
,
U. Knüpfer
,
C. Hertweck
Angewandte Chemie
2008
Corpus ID: 42189092
Complex polyketide metabolites, such as macrolides, polyenes, and polyethers, are an important source of novel therapeutics or…
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2008
2008
Synthetic Strategy of Nonreducing Iterative Polyketide Synthases and the Origin of the Classical “Starter‐Unit Effect”
J. Crawford
,
A. Vagstad
,
Karen Whitworth
,
K. Ehrlich
,
C. Townsend
ChemBioChem
2008
Corpus ID: 10709777
Polyketides isolated from fungi are typically derived from “iterative” Type I (multidomainal) polyketide synthases (PKSs), where…
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2007
2007
PCR screening reveals unexpected antibiotic biosynthetic potential in Amycolatopsis sp. strain UM16
S. A. Wood
,
Bronwyn M. Kirby
,
C. Goodwin
,
M. L. Roes
,
P. Meyers
Journal of Applied Microbiology
2007
Corpus ID: 27799490
Aims: To assess the antibiotic biosynthetic potential of Amycolatopsis sp. strain UM16 and eight other Amycolatopsis species.
Highly Cited
2007
Highly Cited
2007
Stereoelectronic effects dictate mechanistic dichotomy between Cu(II)-catalyzed and enzyme-catalyzed reactions of malonic acid half thioesters.
K. C. Fortner
,
M. Shair
Journal of the American Chemical Society
2007
Corpus ID: 43830151
Previously we developed a Cu(II)-catalyzed, enantioselective aldol reaction between malonic acid half thioesters (MAHTs) and…
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Review
2003
Review
2003
Strategies for combinatorial biosynthesis with modular polyketide synthases.
S. Donadio
,
M. Sosio
Combinatorial chemistry & high throughput…
2003
Corpus ID: 44971067
Polyketides are assembled by the polyketide synthases (PKS) through a common mechanism, the condensation of small carboxylic…
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Highly Cited
2002
Highly Cited
2002
Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways.
A. Trefzer
,
G. Blanco
,
+8 authors
J. Salas
Journal of the American Chemical Society
2002
Corpus ID: 22951255
Heterologous expression of the urdGT2 gene from the urdamycin producer Streptomyces fradiae Tü2717, which encodes a C…
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2002
2002
Bitungolides A-F, new polyketides from the Indonesian sponge Theonella cf. swinhoei.
Sodngam Sirirath
,
J. Tanaka
,
+6 authors
T. Higa
Journal of Natural Products
2002
Corpus ID: 20050812
Six new polyketides, bitungolides A-F (1-6), have been isolated from the Indonesian sponge Theonella cf. swinhoei and their…
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2001
2001
Molecular basis of Celmer's rules: role of the ketosynthase domain in epimerisation and demonstration that ketoreductase domains can have altered product specificity with unnatural substrates.
I. Holzbaur
,
A. Ranganathan
,
+5 authors
P. Leadlay
Chemistry and Biology
2001
Corpus ID: 25942450
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