PolyHeme
National Institutes of Health
Papers overview
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BACKGROUND
Because total hemoglobin in circulation ([THb]) is an established predictor of clinical outcomes in anemic individuals…
Hemoglobin-based oxygen carriers (HBOCs) may be useful in the early treatment of hemorrhagic shock when stored blood is not…
AbstractAim:To investigate the role of death-associated protein kinase (DAPK) on the apoptosis of Raji cells induced by sodium…
Issue of ‘no consent’ raises fundamental questions.
Blood substitutes based on hemoglobin or hemoglobin-based oxygen carriers (HBOCs) are oxygen-carrying therapeutic agents…
Northfield is developing PolyHeme, a solution of polymerized hemoglobin, as a potential blood substitute for use following…
Objective: To review the human and veterinary literature on the current development and use of hemoglobin-based oxygen-carrying…
BACKGROUND: Acute chest syndrome (ACS) is a complication of sickle cell disease that can cause significant morbidity. Transfusion…
BACKGROUND
Resuscitation with oxygen-carrying fluids is critically important in the patient with hemorrhagic shock caused by…