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Second-generation blood tests to detect erythropoietin abuse by athletes.
The increased stability of the new blood parameters facilitates transport of samples to central laboratories, and the heightened sensitivity of thenew models makes them better than existing models for federations wishing to screen samples for urine testing and to identify and target suspect athletes for out-of-competition testing.
Simulated moderate altitude elevates serum erythropoietin but does not increase reticulocyte production in well-trained runners
It is concluded that when daily training loads are controlled, the modest increases in sEpo known to occur following brief exposure to a simulated altitude of 2650 m are insufficient to stimulate reticulocyte production.
Development of reference ranges in elite athletes for markers of altered erythropoiesis.
Assessment of an athlete's blood parameters and ON- and OFF-model scores may need adjustment for training modalities and other characteristics of the subject.
Physiological and pharmacological regulation of 20-kDa growth hormone.
- K. Leung, C. Howe, Lily Y-Y Gui, G. Trout, J. Veldhuis, K. Ho
- Biology, MedicineAmerican journal of physiology. Endocrinology and…
- 1 October 2002
The 20-kDa GH level is reduced by administration of exogenous 22-k da GH, suggesting rapid negative feedback regulation on pituitary release and is cosecreted with and circulates at a constant proportion of 22- kDa GH.
Sports drug testing--an analyst's perspective.
An overview of drug testing procedures, including those that were used at the last summer Olympic Games in Sydney 2000, and the incorporation of the latest developments in analytical chemistry technology in the drug testing process are given.
Determination of urinary steroid sulfate metabolites using ion paired extraction.
Rapid screening method for diuretics in doping control using automated solid phase extraction and liquid chromatography-electrospray tandem mass spectrometry
Influence of demographic factors and sport type on growth hormone-responsive markers in elite athletes.
Age and gender were major determinants of variability of GH-responsive markers except for IGFBP-3 and ALS; however, ethnicity is unlikely to confound the validity of a GH doping test based on IGF-I and these collagen markers.
Carbon isotope ratio (δ13C) values of urinary steroids for doping control in sport