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Organ injury scaling: spleen and liver (1994 revision).
Epidemiology of trauma deaths: a reassessment.
There was an improved access to the medical system, greater proportion of late deaths due to brain injury and lack of the classic trimodal distribution in the Denver City and County trauma system, in comparison with the previous report.
Organ injury scaling: spleen, liver, and kidney.
The Organ Injury Scaling (O.I.S.) Committee of the American Association for the Surgery of Trauma (A.A.S.T.) was appointed by President Trunkey at the 1987 Annual Meeting to devise injury severity scores for individual organs to facilitate clinical research.
Organ injury scaling, II: Pancreas, duodenum, small bowel, colon, and rectum.
The Organ Injury Scaling (O.I.S.) Committee of the American Association for the Surgery of Trauma (A.A.S.T.) has been charged to devise injury severity scores for individual organs to facilitate…
A genomic storm in critically injured humans
It is shown that critical injury in humans induces a genomic storm with simultaneous changes in expression of innate and adaptive immunity genes that alter the status of these genes in the immune system.
Tissue plasminogen activator (tPA) treatment for COVID‐19 associated acute respiratory distress syndrome (ARDS): A case series
- Janice Wang, N. Hajizadeh, C. D. Barrett
- MedicineJournal of thrombosis and haemostasis : JTH
- 8 April 2020
A series of three patients with severe COVID‐19 respiratory failure who were treated with tissue plasminogen activator had a temporally related improvement in their respiratory status, with one of them being a durable response.
The devastating potential of blunt vertebral arterial injuries.
Blunt vertebral arterial injuries are more common than previously reported and systemic anticoagulation appears to be effective therapy: it appears to prevent progression to a higher injury grade, stroke, and deterioration in neurologic status.
The role of chronic alcohol abuse in the development of acute respiratory distress syndrome in adults.
A prior history of chronic alcohol abuse significantly increases the risk of developing ARDS in critically ill patients with an identified at-risk diagnosis, and these results may be useful in the earlier and more accurate identification of patients at high risk for developing AR DS.
Genomic responses in mouse models poorly mimic human inflammatory diseases
- J. Seok, H. S. Warren, R. Tompkins
- BiologyProceedings of the National Academy of Sciences
- 11 February 2013
This study shows that, although acute inflammatory stresses from different etiologies result in highly similar genomic responses in humans, the responses in corresponding mouse models correlate poorly with the human conditions and also, one another.
Structural organization of the neutrophil NADPH oxidase: phosphorylation and translocation during priming and activation
- F. Sheppard, M. Kelher, E. Moore, N. McLaughlin, A. Banerjee, C. Silliman
- BiologyJournal of leukocyte biology
- 1 November 2005
This review will discuss the individual components associated with the NADPH oxidase complex and the function of each of these units in each physiologic stage of the PMN: rested, primed, and activated.