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Poly I-C

Known as: 5'-Inosinic acid, homopolymer, complex with 5'-cytidylic acid homopolymer (1:1), polyinosate-polycytidylate, polyinosate.polycytidylate 
A synthetic polyinosinic-polycytidylic acid double-stranded RNA. Poly IC may stimulate the release of cytotoxic cytokines and, by inducing interferon… 
National Institutes of Health

Related topics

Related topics

15 relations

Broader (3)

Antiviral AgentsInterferon InducersPolynucleotides
In BloodNCIt Antineoplastic Agent TerminologyProcess of secretionagonists

Narrower (4)

Rintatolimodpoly I-5-mercapto-poly Cpoly IC-polylysine carboxymethyl dextranpoly ICLC

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Curvature-Directed Crystallization of Poly(vinylidene difluoride) in Nanotube Walls
Poly(vinylidene difluoride) (PVDF) nanotubes were prepared by wetting of ordered porous templates. We processed either PVDF melts… 
Highly Cited
1999
Highly Cited
1999
ERK activation protects against DNA damage and apoptosis in hyperoxic rat AEC2.
The survival of type 2 alveolar epithelial cells (AEC2) in the lung after hyperoxic injury is regulated by signals from the… 
Highly Cited
1998
Highly Cited
1998
The Reactive Polymeric Micelle Based on An Aldehyde-Ended Poly(ethylene glycol)/Poly(lactide) Block Copolymer
Formation of amphiphilic poly(ethylene glycol)-b-polylactide (PEG/PLA) block copolymers was accomplished by using potassium… 
Highly Cited
1993
Highly Cited
1993
L-14 lectin recognition of laminin and its promotion of in vitro cell adhesion.
The S-type lactose-binding lectins are found in a variety of animal tissues and their primary sequences are highly conserved… 
Highly Cited
1972
Highly Cited
1972
Lac operator analogues: bromodeoxyuridine substitution in the lac operator affects the rate of dissociation of the lac repressor.
As measured by a decreased rate of dissociation, lac repressor binds 10-times tighter to 5-bromodeoxyuridine-substituted lac… 
Highly Cited
1971
Highly Cited
1971
Preparation of sepharose-bound poly (rI:rC).
Highly Cited
1970
Highly Cited
1970
Studies on the binding of actinomycin D to DNA and DNA model polymers.
Highly Cited
1970
Highly Cited
1970
Structure of nucleic acid-poly base complexes.
Highly Cited
1970
Highly Cited
1970
Linkage between the poly-L-lysine gene and the locus controlling the major histocompatibility antigens in strain 2 guinea pigs.
The data presented demonstrate linkage between the major histocompatibility locus of inbred strain 2 guinea pigs and a "specific… 
Highly Cited
1965
Highly Cited
1965
Base interactions of nucleotide polymers in aqueous solution.
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