Skip to search formSkip to main contentSkip to account menu

Point Mutation

Known as: Mutation, Point, Mutations, Point, Point Mutations 
A small-scale mutation in which a single nucleotide is exchanged for another. Mutagenic chemicals and mistakes in DNA replication may result in point… 
National Institutes of Health

Related topics

Related topics

8 relations
F5 Leiden AlleleMissense MutationTransition MutationTransversion Mutation

Broader (2)

Gene MutationMutation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Severity of osteogenesis imperfecta and structure of a collagen-like peptide modeling a lethal mutation site.
We show that there are correlations between the severities of osteogenesis imperfecta (OI) phenotypes and changes in the residues… 
1998
1998
Characterization of the Mitochondrial Genome in Childhood Multiple Sclerosis
Leber's 
1996
1996
Single somatic ras gene point mutation in soft tissue malignant fibrous histiocytomas.
The frequency of ras gene mutations in human soft tissue malignant fibrous histiocytomas within and around the hot spot codons… 
1991
1991
Phospholipase C-delta gene of the spontaneously hypertensive rat harbors point mutations causing amino acid substitutions in a catalytic domain.
This study was undertaken in order to investigate the newly discovered spontaneously hypertensive rat (SHR)-specific restriction… 
Highly Cited
1986
Highly Cited
1986
Sequence specificity of point mutations induced during passage of a UV-irradiated shuttle vector plasmid in monkey cells
A simian virus 40-based shuttle vector was used to characterize UV-induced mutations generated in mammalian cells. The small size… 
1986
1986
High rate of somatic point mutation in vitro in and near the variable-region segment of an immunoglobulin heavy chain gene.
The "silent" allele at the immunoglobulin heavy-chain locus in the pre-B-lymphocyte line 18-81 contains a correctly assembled… 
Highly Cited
1986
Highly Cited
1986
Mutational analysis of the immunoglobulin heavy chain promoter region.
Complete immunoglobulin heavy chain (IgH) genes (gamma and mu) containing the intronic IgH enhancer and mutations in the upstream… 
1980
1980
Segment-directed mutagenesis: construction in vitro of point mutations limited to a small predetermined region of a circular DNA molecule.
A general method for efficiently mutagenizing a predetermined segment of a closed circular duplex DNA molecule was used to… 
1979
1979
Possible point mutation sites in LSc, 2ab poliovirus RNA and a protein covalently linked to the 5'-terminus.
Poliovirus type I, vaccine strain (LSc, 2ab), which is a temperature- and actinomycin D-sensitive mutant derived from type I… 
1975
1975
Mutation induction by difunctional alkylating agents in Neurospora crassa.
The genetic characterization of ad-3 mutants of Neurospora crassa induced by two carcinogenic difunctional akylating agents, 1,2…