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Point Mutation

Known as: Mutation, Point, Mutations, Point, Point Mutations 
A small-scale mutation in which a single nucleotide is exchanged for another. Mutagenic chemicals and mistakes in DNA replication may result in point… Expand
National Institutes of Health

Papers overview

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Review
2016
Review
2016
Parkinson's disease is a neurodegenerative disease/synucleinopathy that develops slowly; however, there is no efficient method of… Expand
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Myelodysplastic syndromes are clinically heterogeneous disorders characterized by clonal hematopoiesis, impaired… Expand
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Patients with non-small-cell lung cancer harbouring mutations in the epidermal growth factor receptor (EGFR) gene… Expand
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Highly Cited
1994
Highly Cited
1994
Mice homozygous for lpr (lymphoproliferation) or gld (generalized lymphoproliferative disease) develop lymphadenopathy and suffer… Expand
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Highly Cited
1994
Highly Cited
1994
ACTIVATED protein C (APC) is a serine protease with potent anti-coagulant properties, which is formed in blood on the endothelium… Expand
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Highly Cited
1993
Highly Cited
1993
Genetic and metabolic studies have been done on a large kindred in which several males are affected by a syndrome of borderline… Expand
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Highly Cited
1992
Highly Cited
1992
We examined somatic mutations of the adenomatous polyposis coli (APC) gene in 63 colorectal tumors (16 adenomas and 47 carcinomas… Expand
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Highly Cited
1991
Highly Cited
1991
A LOCUS segregating with familial Alzheimer's disease (AD) has been mapped to chromosome 21 (ref. 1), close to the amyloid… Expand
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Highly Cited
1989
Highly Cited
1989
We have improved the "polymerase chain reaction" (PCR) to permit rapid analysis of any known mutation in genomic DNA. We… Expand
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Highly Cited
1989
Highly Cited
1989
The mdx mouse is an X-linked myopathic mutant, an animal model for human Duchenne muscular dystrophy. In both mouse and man the… Expand
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