Platelet Glycoprotein GPIIb-IIIa Complex

Known as: Alpha 2b/Beta 3, Glycoprotein IIb/IIIa, Alpha2b/Beta3 
Platelet membrane glycoprotein complex important for platelet adhesion and aggregation. It is an integrin complex containing INTEGRIN ALPHAIIB and… (More)
National Institutes of Health

Papers overview

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Highly Cited
2002
Highly Cited
2002
RATIONALE AND OBJECTIVES New targeted microbubbles directed to the GPIIb IIIa receptor have been developed. The objective was to… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND In the setting of percutaneous coronary revascularization, agents in the class known as platelet glycoprotein IIb/IIIa… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Both inherited predisposition and platelet hyperreactivity have been associated with ischemic coronary events, but… (More)
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Highly Cited
1998
Highly Cited
1998
T cell proliferative responses to platelet membrane GPIIb-IIIa were examined in 14 patients with chronic immune thrombocytopenic… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND Blockade of the platelet glycoprotein IIb/IIIa receptor with abciximab (a monoclonal-antibody Fab fragment directed… (More)
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Highly Cited
1997
Highly Cited
1997
Recent clinical trials suggest that blockade of integrins is a promising strategy for the treatment of acute coronary syndromes… (More)
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Highly Cited
1996
Highly Cited
1996
BACKGROUND Platelet glycoprotein IIb/IIIa is a membrane receptor for fibrinogen and von Willebrand factor, and it has an… (More)
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Highly Cited
1994
Highly Cited
1994
Platelet aggregation, which plays an important role in acute myocardial infarction (AMI), is mediated by fibrinogen binding to… (More)
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Highly Cited
1985
Highly Cited
1985
Considerable evidence indicates that the glycoprotein (GP) IIb/IIIa complex on human platelets functions as a receptor for… (More)
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Highly Cited
1984
Highly Cited
1984
Chronic idiopathic thrombocytopenic purpura (ITP) is caused by an antibody reactive with platelet-associated antigens. The… (More)
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