Skip to search formSkip to main contentSkip to account menu

Platelet Glycoprotein GPIIb-IIIa Complex

Known as: Alpha 2b/Beta 3, Glycoprotein IIb/IIIa, Alpha2b/Beta3 
Platelet membrane glycoprotein complex important for platelet adhesion and aggregation. It is an integrin complex containing INTEGRIN ALPHAIIB and… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1997
Highly Cited
1997
BACKGROUND The glycoprotein (GP) IIb/IIIa receptor antagonist abciximab (c7E3 Fab, ReoPro) is approved for use in high-risk… 
Highly Cited
1997
Highly Cited
1997
Glanzmann thrombasthenia, an inherited bleeding disorder, can be caused by a defect or deficiency in platelet integrin alphaIIb… 
Highly Cited
1994
Highly Cited
1994
Platelet adhesion to purified surface-immobilized fibronectin under flow conditions was investigated. Fibronectin was found to… 
Highly Cited
1993
Highly Cited
1993
To speed drug discovery, we developed an approach for identification of individual peptides with a desired biological activity… 
Highly Cited
1992
Highly Cited
1992
We demonstrate an example of signal transduction by an integrin and have begun to define the pathway through which this signaling… 
Highly Cited
1991
Highly Cited
1991
BackgroundThe comparative effects of aspirin and F(ab′)2 fragments of monoclonal antibody 7E3 against the platelet glycoprotein… 
Highly Cited
1990
Highly Cited
1990
We have previously observed calpain activity (calcium‐dependent cysteine protease) in sera from patients with acute thrombotic… 
Highly Cited
1986
Highly Cited
1986
We studied the effects(s) of two monoclonal antibodies, 6D1 and 10E5 (directed against platelet glycoprotein Ib [GPIb] and the…