FAQ

Platelet Glycoprotein 4, human

Known as: GPIIIB, CD36, Platelet Collagen Receptor 
Platelet glycoprotein 4 (472 aa, ~53 kDa) is encoded by the human CD36 gene. This protein is involved in blood coagulation, fatty acid binding, and… (More)

Topic mentions per year

Topic mentions per year

1971-2018
020406019712018

Related topics

Related topics

19 relations
Adipocytokine Signaling PathwayAngiogenic ProcessCD36 geneCD36 wt Allele
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Broader (1)

CD36 Antigens

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Platelet Glycoprotein 4, human
Cell Adhesion
Lipid Metabolism
Homo sapiens
Tumor Markers
protein protein interaction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation
Particulate ligands, including cholesterol crystals and amyloid fibrils, induce production of interleukin 1β (IL-1β) dependent on… (More)
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Highly Cited
2008
Highly Cited
2008
Robust single particle tracking in live cell time-lapse sequences
Single-particle tracking (SPT) is often the rate-limiting step in live-cell imaging studies of subcellular dynamics. Here we… (More)
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Highly Cited
2008
Highly Cited
2008
Hepatic fatty acid transporter Cd36 is a common target of LXR, PXR, and PPARgamma in promoting steatosis.
BACKGROUND & AIMS Liver X receptor (LXR) is known to promote hepatic lipogenesis by activating the lipogenic transcriptional… (More)
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Highly Cited
2008
Highly Cited
2008
Synuclein activates microglia in a model of Parkinson's disease.
Parkinson's disease (PD) is the most common neurodegenerative movement disorder afflicting >500,000 patients in the United States… (More)
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Highly Cited
2007
Highly Cited
2007
Platelet CD36 links hyperlipidemia, oxidant stress and a prothrombotic phenotype
Dyslipidemia is associated with a prothrombotic phenotype; however, the mechanisms responsible for enhanced platelet reactivity… (More)
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Highly Cited
2006
Highly Cited
2006
A CD36-dependent signaling cascade is necessary for macrophage foam cell formation.
Accumulation of macrophage foam cells in atherosclerotic blood vessel intima is a critical component of atherogenesis mediated by… (More)
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Highly Cited
2005
Highly Cited
2005
Loss of receptor-mediated lipid uptake via scavenger receptor A or CD36 pathways does not ameliorate atherosclerosis in hyperlipidemic mice.
Macrophage internalization of modified lipoproteins is thought to play a critical role in the initiation of atherogenesis. Two… (More)
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Highly Cited
2002
Highly Cited
2002
CD36, a class B scavenger receptor, is expressed on microglia in Alzheimer's disease brains and can mediate production of reactive oxygen species in response to beta-amyloid fibrils.
A pathological hallmark of Alzheimer's disease is the senile plaque, composed of beta-amyloid fibrils, microglia, astrocytes, and… (More)
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Highly Cited
2000
Highly Cited
2000
Acute regulation of fatty acid uptake involves the cellular redistribution of fatty acid translocase.
We used muscle contraction, which increases fatty acid oxidation, as a model to determine whether fatty acid transport is acutely… (More)
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Highly Cited
1994
Highly Cited
1994
Expression cloning of SR-BI, a CD36-related class B scavenger receptor.
Scavenger receptors are integral membrane proteins that mediate the endocytosis of modified lipoproteins. The first of these to… (More)
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