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Platelet Activating Factor

Known as: platelet activating factor (PAF), 1 Alkyl 2 acetyl sn glycerophosphocholine, Thrombocyte Aggregating Activity 
A phospholipid derivative formed by PLATELETS; BASOPHILS; NEUTROPHILS; MONOCYTES; and MACROPHAGES. It is a potent platelet aggregating agent and… 
National Institutes of Health

Related topics

Related topics

15 relations

Broader (3)

Blood Coagulation FactorPhospholipid Etherscytokine

Narrower (3)

ONO 6240U 66985dansyl-platelet activating factor
Process of secretionagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

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Review
1995
Review
1995
Platelet-activating factor antagonists
ConclusionsThe great number of PAF antagonists reviewed in this article clearly shows the tremendous effort made in the last 20… 
1995
1995
Provocation testing in clinical practice
Allergenic Extracts, John W. Yunginger Standardization of Allergens, Jean Bousquet and Fran ois-B. Michel Use of the Skin Blister… 
Highly Cited
1986
Highly Cited
1986
Platelet-activating factor causes pulmonary vasodilation in the rat.
Although platelet-activating factor (PAF) has generally been found to be a pulmonary pressor substance, its vasoactivity has not… 
Review
1985
Review
1985
A role for PAF-acether (platelet-activating factor) in platelet-dependent vascular diseases?
Platelets-isolated or in conjunction with leukocytes-interact with vessel walls in many experimental and human diseases. Several… 
Highly Cited
1984
Highly Cited
1984
Isolation of a platelet membrane protein which binds the platelet-activating factor 1-0-hexadecyl-2-acetyl-SN-glycero-3-phosphorylcholine.
The phospholipid platelet-activating factor 1-0-hexadecyl-2-acetyl-SN-glycero-3-phosphorylcholine (AGEPC) initiates platelet… 
1984
1984
Possible role of endothelium in the vasodilator response of rat thoracic aorta to platelet activating factor (PAF).
As the endothelium has an important role in the vasodilating effect of acetylcholine, we investigated the possible role of the… 
Highly Cited
1981
Highly Cited
1981
Modification of the polar head group of acetyl glyceryl ether phosphorylcholine and subsequent effects upon platelet activation.
A series of phosphoglycerides containing the same structural unit, 1-O-alkyl-2-acetyl-sn-glycerol, was prepared with the… 
1980
1980
The binding of rabbit basophil-derived platelet-activating factor to rabbit platelets.
The platelet binding characteristics of platelet-activating factor (PAF), a basophil-derived lipid that causes aggregation and… 
Highly Cited
1977
Highly Cited
1977
Release of platelet-activating factor and histamine. I. Effect of immune complexes, complement and neutrophils on human and rabbit mastocytes and basophils.
Immune complexes (ICs) triggered the degranulation of basophils/mastocytes in rabbit and man, thus releasing histamine and… 
Highly Cited
1973
Highly Cited
1973
Plasma aggregating factor (bovine) for human platelets: a marker for study of antihemophilic and von Willebrand Factors.
The human-platelet aggregating factor in preparations of bovine plasma and bovine antihemophilic factor has been reported to be…